Evidence map›Paper›PMID 30869000›Full record

SynthesisEpidemiology and infection2019

Global status of Middle East respiratory syndrome coronavirus in dromedary camels: a systematic review.

R S Sikkema, E A B A Farag, Mazharul Islam, Muzzamil Atta, C B E M Reusken, Mohd M Al-Hajri, M P G Koopmans

Erratum issuedOpen access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 53 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 4 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 4 syntheses or guidelines pooled it, 90 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Article
  7. Article
  8. Pneumo-/enteritis in dromedary camels (Frontiers in veterinary science · 2026
    Review
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  11. Article
  12. Review
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  15. Article
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  20. Pandemic origins and a One Health approach to preparedness and prevention: Solutions based on SARS-CoV-2 and other RNA viruses.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

R S SikkemaDepartment of Viroscience,Erasmus University Medical Center,Rotterdam,The Netherlands.ORCID 0000-0001-7331-6274
E A B A FaragMinistry of Public of Health,Doha,Qatar.
Mazharul IslamDepartment of Animal Resources,Ministry of Municipality and Environment,Doha,Qatar.
Muzzamil AttaDepartment of Animal Resources,Ministry of Municipality and Environment,Doha,Qatar.
C B E M ReuskenDepartment of Viroscience,Erasmus University Medical Center,Rotterdam,The Netherlands.
Mohd M Al-HajriMinistry of Public of Health,Doha,Qatar.
M P G KoopmansDepartment of Viroscience,Erasmus University Medical Center,Rotterdam,The Netherlands.
Erasmus MC · NLMinistry of Environment and Climate Change · QAMinistry of Public Health · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dromedary camels have been shown to be the main reservoir for human Middle East respiratory syndrome (MERS) infections. This systematic review aims to compile and analyse all published data on MERS-coronavirus (CoV) in the global camel population to provide an overview of current knowledge on the distribution, spread and risk factors of infections in dromedary camels. We included original research articles containing laboratory evidence of MERS-CoV infections in dromedary camels in the field from 2013 to April 2018. In general, camels only show minor clinical signs of disease after being infected with MERS-CoV. Serological evidence of MERS-CoV in camels has been found in 20 countries, with molecular evidence for virus circulation in 13 countries. The seroprevalence of MERS-CoV antibodies increases with age in camels, while the prevalence of viral shedding as determined by MERS-CoV RNA detection in nasal swabs decreases. In several studies, camels that were sampled at animal markets or quarantine facilities were seropositive more often than camels at farms as well as imported camels vs. locally bred camels. Some studies show a relatively higher seroprevalence and viral detection during the cooler winter months. Knowledge of the animal reservoir of MERS-CoV is essential to develop intervention and control measures to prevent human infections.

Indexed as

CamelusCoronavirus InfectionsZoonosesAnimalsMiddle East Respiratory Syndrome CoronavirusAnimal pathogenscoronavirusemerging infectionszoonoses

Identifiers

PMID30869000
PMCPMC6518605
OpenAlexW2918021248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.