ArticleJournal of biomedical optics2019
Real-time, wide-field, and quantitative oxygenation imaging using spatiotemporal modulation of light.
Article in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Noninvasive hemoglobin sensing and imaging: optical tools for disease diagnosis.Journal of biomedical optics · 2022Pooled it
- TRIDENT: inTRaoperative Imaging DEvice based on endogeNous opTical properties to evaluate bowel oxygenation in left-sided colorectal resections. Observational first-in-human pilot safety trial.Surgical endoscopy · 2026Article
- Intelligent delignification: leveraging explainable AI for ozone transport modeling and optimization.Scientific reports · 2025Article
- Soybean seed pest damage detection method based on spatial frequency domain imaging combined with RL-SVM.Plant methods · 2024Article
- Quantification of bowel ischaemia using real-time multispectral Single Snapshot Imaging of Optical Properties (SSOP).Surgical endoscopy · 2023Article
- Article
- Spatial Frequency Domain Imaging System Calibration, Correction and Application for Pear Surface Damage Detection.Foods (Basel, Switzerland) · 2021Article
- Imaging sub-diffuse optical properties of cancerous and normal skin tissue using machine learning-aided spatial frequency domain imaging.Journal of biomedical optics · 2021Article
- Rapid tissue oxygenation mapping from snapshot structured-light images with adversarial deep learning.Journal of biomedical optics · 2020Article
- Real-time optical properties and oxygenation imaging using custom parallel processing in the spatial frequency domain.Biomedical optics express · 2019Article
- Special Section Guest Editorial: Special Section on Spatial Frequency Domain Imaging.Journal of biomedical optics · 2019Article
- Spatial frequency domain imaging in 2019: principles, applications, and perspectives.Journal of biomedical optics · 2019Review
- Single snapshot imaging of optical properties using a single-pixel camera: a simulation study.Journal of biomedical optics · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Quantitative diffuse optical imaging has the potential to provide valuable functional information about tissue status, such as oxygen saturation or blood content to healthcare practitioners in real time. However, significant technical challenges have so far prevented such tools from being deployed in the clinic. Toward achieving this goal, prior research introduced methods based on spatial frequency domain imaging (SFDI) that allow real-time (within milliseconds) wide-field imaging of optical properties but at a single wavelength. However, for this technology to be useful to clinicians, images must be displayed in terms of metrics related to the physiological state of the tissue, hence interpretable to guide decision-making. For this purpose, recent developments introduced multispectral SFDI methods for rapid imaging of oxygenation parameters up to 16 frames per seconds (fps). We introduce real-time, wide-field, and quantitative blood parameters imaging using spatiotemporal modulation of light. Using this method, we are able to quantitatively obtain optical properties at 100 fps at two wavelengths (665 and 860 nm), and therefore oxygenation, oxyhemoglobin, and deoxyhemoglobin, using a single camera with, at most, 4.2% error in comparison with standard SFDI acquisitions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.