Evidence map›Paper›PMID 30868446›Full record

ArticleMolecular neurobiology2019

A Novel PEGylated Block Copolymer in New Age Therapeutics for Alzheimer's Disease.

Sutapa Som Chaudhury, Achinta Sannigrahi, Mridula Nandi, Vipin K Mishra, Priyadarsi De, Krishnananda Chattopadhyay, Sabyashachi Mishra, Jaya Sil, Chitrangada Das Mukhopadhyay

Abstract read
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In one paragraph

Article in Molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sutapa Som ChaudhuryCentre for Healthcare Science and Technology, IIEST, Shibpur, P.O. Botanic Garden, Howrah, West Bengal, 711103, India.
Achinta SannigrahiStructural Biology & Bioinformatics Division, CSIR-IICB, Kolkata, 4, S.C. Mallick Road, Jadavpur, Kolkata, West Bengal, 700032, India.
Mridula NandiDepartment of Chemical Sciences, IISER Kolkata, Mohanpur, Nadia, West Bengal, 741246, India.
Vipin K MishraDepartment of Chemistry, IIT Kharagpur, Kharagpur, West Bengal, 721302, India.
Priyadarsi DeDepartment of Chemical Sciences, IISER Kolkata, Mohanpur, Nadia, West Bengal, 741246, India.
Krishnananda ChattopadhyayStructural Biology & Bioinformatics Division, CSIR-IICB, Kolkata, 4, S.C. Mallick Road, Jadavpur, Kolkata, West Bengal, 700032, India.
Sabyashachi MishraDepartment of Chemistry, IIT Kharagpur, Kharagpur, West Bengal, 721302, India.
Jaya SilCentre for Healthcare Science and Technology, IIEST, Shibpur, P.O. Botanic Garden, Howrah, West Bengal, 711103, India.
Chitrangada Das MukhopadhyayCentre for Healthcare Science and Technology, IIEST, Shibpur, P.O. Botanic Garden, Howrah, West Bengal, 711103, India. chitrangadam@chest.iiests.ac.in.ORCID http://orcid.org/0000-0002-7245-4736

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The amyloid cascade hypothesis dealing with the senile plaques is until date thought to be one of the causative pathways leading to the pathophysiology of Alzheimer's disease (AD). Though many aggregation inhibitors of misfolded amyloid beta (Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesCell DeathCell Line, TumorCell SurvivalHumansLigandsMolecular Dynamics SimulationPolyethylene GlycolsStatic ElectricityAmyloid beta-PeptidesLigandsPolyethylene GlycolsAlzheimer’s diseaseAmyloid beta peptideFibrillizationInhibitorM.D. simulationPeptidomimetics

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.