ReviewAnnals of intensive care2019
Narrative review: clinical assessment of peripheral tissue perfusion in septic shock.
Review in Annals of intensive care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it, 198 citations in OpenAlex.
- Meta-Analysis of the Prognostic Value of Skin Perfusion Parameters in Sepsis Patients: Evidence Integration Based on the Mottling Score, Capillary Refill Time, and Peripheral Perfusion Index.Shock (Augusta, Ga.) · 2026Pooled it
- [Relationship between cardiac output, heart rate and microcirculation in patients with multiorgan dysfunction syndrome].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2024Trial
- Implementation of hyperspectral imaging in a trauma resuscitation room: a randomized controlled trial.Scandinavian journal of trauma, resuscitation and emergency medicine · 2022Trial
- Effects of nitroglycerin versus labetalol on peripheral perfusion during deliberate hypotension for sinus endoscopic surgery: a randomized, controlled, double-blinded trial.BMC anesthesiology · 2020Trial
- [Elevation of red blood cell distribution width to hematocrit ratio is associated with increased 28-day all-cause mortality in septic patients].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- The evolution of sepsis care: from protocol-driven management to personalized intensive care.Infection · 2026Review
- Clinical criteria for the definition of refractory septic shock: a joint Delphi consensus from the Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM).Intensive care medicine · 2026Article
- Impaired tissue perfusion in high-risk patients having major abdominal surgery: a multicenter observational study.Critical care (London, England) · 2026Observational
- Less-Invasive Hemodynamic and Tissue Perfusion Monitoring in Sepsis and Septic Shock: A Narrative Review.Journal of clinical medicine · 2026Review
- The Physiology, Pathophysiology, and Clinical Implications of Fluid Resuscitation in Critically Ill Patients.Cureus · 2026Review
- Pilot phase clinical trial of a wearable, electrochemical aptamer-based patch for continuous drug concentration measurement.Nature biotechnology · 2026Article
- Bridging sepsis physiology and biosensor engineering: a clinical perspective on electrochemical cytokine sensor design.Frontiers in bioengineering and biotechnology · 2026Article
- Septic shock in the era of precision medicine: rethinking fluids, vasopressors, and immunomodulation.Frontiers in medicine · 2026Review
- Application of Infrared Thermography in Early Screening of Sepsis and Prediction of Septic Shock Risk: A Systematic Review.Emergency medicine international · 2026Review
- Impact of 30 mL/kg fluid resuscitation completed within one hour on elderly septic shock patient.Annals of medicine · 2025Observational
- Multimodal assessment of peripheral perfusion in critically ill patients: a pilot study.Annals of intensive care · 2025Article
- A Novel Approach to Early Personalized Hemodynamic Resuscitation: Non-Invasive Peripheral Photoplethysmography for Identifying Predominant Vasodilatory Shock in Sepsis.Acta anaesthesiologica Scandinavica · 2025Article
- The intricate relationship between capillary refill time and systemic hemodynamics in septic shock.Annals of intensive care · 2025Review
- The Usefulness of Peripheral and Organ Perfusion Monitoring in Predicting Mortality in Patients with Severe SARS-CoV-2.Biomedicines · 2025Article
- The Predictive Value of Clinical Signs to Identify Shock in Critically Ill Patients.Diagnostics (Basel, Switzerland) · 2025Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sepsis is one of the main reasons for intensive care unit admission and is responsible for high morbidity and mortality. The usual hemodynamic targets for resuscitation of patients with septic shock use macro-hemodynamic parameters (hearth rate, mean arterial pressure, central venous pressure). However, persistent alterations of microcirculatory blood flow despite restoration of macro-hemodynamic parameters can lead to organ failure. This dissociation between macro- and microcirculatory compartments brings a need to assess end organs tissue perfusion in patients with septic shock. Traditional markers of tissue perfusion may not be readily available (lactate) or may take time to assess (urine output). The skin, an easily accessible organ, allows clinicians to quickly evaluate the peripheral tissue perfusion with noninvasive bedside parameters such as the skin temperatures gradient, the capillary refill time, the extent of mottling and the peripheral perfusion index.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.