Evidence map›Paper›PMID 30868250›Full record

ArticleMikrochimica acta2019

A bioinspired antifouling zwitterionic interface based on reduced graphene oxide carbon nanofibers: electrochemical aptasensing of adenosine triphosphate.

Tingting Zhang, Haixin Xu, Zhiqian Xu, Yue Gu, Xiaoyi Yan, He Liu, Nannan Lu, Siyuan Zhang, Zhiquan Zhang, Ming Yang

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tingting ZhangCollege of Chemistry, Jilin University, Changchun, 130012, China.
Haixin XuCollege of Chemistry, Jilin University, Changchun, 130012, China.
Zhiqian XuCollege of Chemistry, Jilin University, Changchun, 130012, China.
Yue GuCollege of Chemistry, Jilin University, Changchun, 130012, China.
Xiaoyi YanCollege of Chemistry, Jilin University, Changchun, 130012, China.
He LiuCollege of Chemistry, Jilin University, Changchun, 130012, China.
Nannan LuCollege of Chemistry, Jilin University, Changchun, 130012, China.
Siyuan ZhangExperimental School of the Affiliated Middle School to Jilin University, Changchun, 130021, China.
Zhiquan ZhangCollege of Chemistry, Jilin University, Changchun, 130012, China. zzq@jlu.edu.cn.
Ming YangDepartment of Breast Surgery, First Hospital, Jilin University, Changchun, 130012, China. yangming1967@163.com.
Jilin University · CNFirst Hospital of Jilin University · CN

Funding

National Natural Science Foundation of China (CN) 21375045Natural Science Foundation of Jilin Province (CN) 20180101195JC
6 · The paper itself

Abstract

An antifouling electrochemical aptasensor for ATP is described that has a zwitterionic self-assembled sensing interface on a glassy carbon electrode modified with a reduced graphene oxide carbon nanofiber (GO-CNF). The GO-CNF was first modified by self-polymerization of dopamine which provided a platform for simultaneously self-assembly of the ATP aptamer and cysteine. By using hexacyanoferrate as the electrochemical probe, in the presence of ATP, the aptamer strands fold around ATP molecules, thus leading to the variation of the electrochemical signal. The aptasensor has a linear response in the 0.1 pM to 5 nM ATP concentration range, and a 13 fM lower detection limit. The electrode is strongly resistant to nonspecific adsorption and biofouling. This enabled the detection of ATP even in spiked human plasma. Graphical abstract An antifouling electrochemical aptasensor employing reduced graphene oxide carbon nanofiber as conductive substrate and zwitterionic cysteine as antifouling material for adenosine triphosphate detection.

Indexed as

Adenosine TriphosphateAptamers, NucleotideBiosensing TechniquesCysteineDielectric SpectroscopyDNAElectrodesGraphiteHumansLimit of DetectionNanofibersReproducibility of ResultsAdenosine TriphosphateAptamers, NucleotideCysteineDNAgraphene oxideGraphiteBiocompatibilityCysteineDisease biomarkersImpedanceMixed self-assembly

Identifiers

PMID30868250
OpenAlexW2921102487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.