Evidence map›Paper›PMID 30868218›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2019

Fortuitous discovery of non-fluorocholine-fixing papillary carcinoma of vesicular variant of the thyroid.

Nicolas Guignard, Guillaume Chambon, Benjamin Chambert, Yaser Najaf, Benjamin Lallemant

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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nicolas GuignardCentre hospitalo-universitaire de Nîmes, Service d'oto-rhino-laryngologie, Rue du Professeur Robert Debré, 30900, Nîmes, France. nicolasguignard87@gmail.com.ORCID http://orcid.org/0000-0001-5835-1194
Guillaume ChambonCentre hospitalo-universitaire de Nîmes, Service d'oto-rhino-laryngologie, Rue du Professeur Robert Debré, 30900, Nîmes, France.
Benjamin ChambertCentre hospitalo-universitaire de Nîmes, Service de médecine nucléaire, Rue du Professeur Robert Debré, 30900, Nîmes, France.
Yaser NajafCentre hospitalo-universitaire de Nîmes, Service de médecine nucléaire, Rue du Professeur Robert Debré, 30900, Nîmes, France.
Benjamin LallemantCentre hospitalo-universitaire de Nîmes, Service d'oto-rhino-laryngologie, Rue du Professeur Robert Debré, 30900, Nîmes, France.
Centre Hospitalier Universitaire de Nîmes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCharacterization of thyroid nodules is crucial to propose surgical intervention for histological verification. Cervical ultrasound potentially combined with fine needle aspiration is recommended, and fluorocholine positron emission tomography (FCH-PET), commonly used in prostatic cancers, has been evaluated in the diagnosis of thyroid cancers in recent publications.

methodsWe present two cases of patients with multinodular thyroid and primary hyperparathyroidism. The preoperative assessment consisted of an ultrasound, a MIBI scintigraphy and an FCH-PET in favor of a parathyroid adenoma.

resultsThe imaging examinations pointed to a diagnosis of a parathyroid adenoma. In both cases, papillary thyroid carcinoma, missed by FCH-PET, was discovered incidentally at a distance from the parathyroid adenoma during the surgical procedure.

conclusionsThese are the first descriptions of thyroid papillary carcinoma without preoperative FCH-PET identification. These clinical cases are contrary to recent publications showing a benefit of this examination in the diagnosis of thyroid cancers.

Indexed as

Incidental FindingsRadiopharmaceuticalsAgedCholineFemaleHumansMaleMiddle AgedPositron Emission Tomography Computed TomographyThyroid Cancer, PapillaryThyroid NeoplasmsCholinefluorocholineRadiopharmaceuticals18F-Choline PET-CTDifferentiated thyroid cancerPapillary thyroid carcinomaPET-CTThyroid incidentaloma

Identifiers

PMID30868218
OpenAlexW2921074500

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.