ArticleCase reports in endocrinology2019
A Case of Refractory Hypothyroidism due to Poor Compliance Treated with the Weekly Intravenous and Oral Levothyroxine Administration.
Article in Case reports in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Article
- From Resistance to Relief: IV Levothyroxine in Refractory Hypothyroidism Management.Clinical case reports · 2025Article
- Intramuscular and subcutaneous levothyroxine: success in treating refractory hypothyroidism.European thyroid journal · 2025Article
- Medication-Nonadherent Hypothyroidism Requiring Frequent Primary Care Visits to Achieve Euthyroidism.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024Article
- Levothyroxine absorption test followed by directly observed treatment on an outpatient basis to address long-term high thyrotropin levels in a hypothyroid patient: a case report.Journal of medical case reports · 2023Article
- Subcutaneous administration of levothyroxine: a novel approach to refractory hypothyroidism - A review and a case report.Archives of endocrinology and metabolism · 2021Review
- Cardioprotection by post-conditioning with exogenous triiodothyronine in isolated perfused rat hearts and isolated adult rat cardiomyocytes.Basic research in cardiology · 2021Article
- A Case of Refractory Myxedema Coma.Cureus · 2020Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Refractory hypothyroidism is caused by decreased gut absorption, increased metabolism, and poor compliance. Previous studies suggested that the weekly oral, suppository, or intramuscular administration of levothyroxine (LT4) is an effective treatment for refractory hypothyroidism. However, limited information is currently available on treatment involving the weekly intravenous administration of LT4. We managed a case of refractory hypothyroidism due to poor compliance, for which, by weekly intravenous LT4 administration, LT4 was intravenously administered weekly at a dose of 300
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Registered trials
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