Evidence map›Paper›PMID 30867928›Full record

ArticleIUCrJ2019

Fixed-target serial oscillation crystallography at room temperature.

Jennifer L Wierman, Olivier Paré-Labrosse, Antoine Sarracini, Jessica E Besaw, Michael J Cook, Saeed Oghbaey, Hazem Daoud, Pedram Mehrabi, Irina Kriksunov, Anling Kuo and 7 more

Abstract read
In one paragraph

Article in IUCrJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Microfluidic Devices for High-Throughput In Situ Serial Crystallography.Advances in biochemical engineering/biotechnology · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Guide to serial synchrotron crystallography.Current research in structural biology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Room-temperature serial synchrotron crystallography of Drosophila cryptochrome.Acta crystallographica. Section D, Structural biology · 2022
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jennifer L WiermanMacCHESS, Cornell University, Ithaca, NY 14853, USA.
Olivier Paré-LabrosseDepartments of Chemistry and Physics, University of Toronto, Toronto, ON Canada.
Antoine SarraciniDepartments of Chemistry and Physics, University of Toronto, Toronto, ON Canada.ORCID https://orcid.org/0000-0003-2246-815X
Jessica E BesawDepartments of Chemistry and Physics, University of Toronto, Toronto, ON Canada.ORCID https://orcid.org/0000-0002-7571-7132
Michael J CookMacCHESS, Cornell University, Ithaca, NY 14853, USA.
Saeed OghbaeyDepartments of Chemistry and Physics, University of Toronto, Toronto, ON Canada.
Hazem DaoudDepartments of Chemistry and Physics, University of Toronto, Toronto, ON Canada.ORCID https://orcid.org/0000-0002-2616-2484
Pedram MehrabiMax Planck Institute for the Structure and Dynamics of Matter, Hamburg, Germany.
Irina KriksunovMacCHESS, Cornell University, Ithaca, NY 14853, USA.
Anling KuoDepartments of Biochemistry and Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
David J SchullerMacCHESS, Cornell University, Ithaca, NY 14853, USA.
Scott SmithMacCHESS, Cornell University, Ithaca, NY 14853, USA.
Oliver P ErnstDepartments of Biochemistry and Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-8863-9444
Doletha M E SzebenyiMacCHESS, Cornell University, Ithaca, NY 14853, USA.ORCID https://orcid.org/0000-0003-0229-9985
Sol M GrunerMacCHESS, Cornell University, Ithaca, NY 14853, USA.ORCID https://orcid.org/0000-0002-1171-4426
R J Dwayne MillerDepartments of Chemistry and Physics, University of Toronto, Toronto, ON Canada.
Aaron D FinkeMacCHESS, Cornell University, Ithaca, NY 14853, USA.

Funding

Overall (pp. 40-62)P41GM103485 · NIGMS · CORNELL UNIVERSITY · PI CERIONE, RICHARD A. · 2012 to 2018
$15.5M
NIGMS NIH HHS P41 GM103485
6 · The paper itself

Abstract

A fixed-target approach to high-throughput room-temperature serial synchrotron crystallography with oscillation is described. Patterned silicon chips with microwells provide high crystal-loading density with an extremely high hit rate. The microfocus, undulator-fed beamline at CHESS, which has compound refractive optics and a fast-framing detector, was built and optimized for this experiment. The high-throughput oscillation method described here collects 1-5° of data per crystal at room temperature with fast (10° s

Indexed as

fixed-target serial oscillationoscillationsradiation damageserial crystallographystorage ringsstructural biologystructure determinationX-ray crystallography

Identifiers

PMID30867928
PMCPMC6400179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.