Evidence map›Paper›PMID 30867846›Full record

ArticleTheranostics2019

p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.

Yan Zhao, Zhecheng Wang, Dongcheng Feng, Huanyu Zhao, Musen Lin, Yan Hu, Ning Zhang, Li Lv, Zhenming Gao, Xiaohan Zhai and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 97 citations in OpenAlex.

  1. Review
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  16. Article
  17. Progress in the Correlation Between Inflammasome NLRP3 and Liver Fibrosis.Journal of clinical and translational hepatology · 2024
    Review
  18. Article
  19. The p66International journal of molecular sciences · 2023
    Review
  20. Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yan ZhaoDepartment of Pharmacology, Dalian Medical University, Dalian 116044, China.
Zhecheng WangDepartment of Pharmacology, Dalian Medical University, Dalian 116044, China.
Dongcheng FengDepartment of Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian 116023, China.
Huanyu ZhaoDepartment of Pharmacology, Dalian Medical University, Dalian 116044, China.
Musen LinDepartment of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian 116023, China.
Yan HuDepartment of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian 116023, China.
Ning ZhangDepartment of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian 116023, China.
Li LvDepartment of Pharmacology, Dalian Medical University, Dalian 116044, China.
Zhenming GaoDepartment of Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian 116023, China.
Xiaohan ZhaiDepartment of Pharmacy, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
Xiaofeng TianDepartment of Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian 116023, China.
Jihong YaoDepartment of Pharmacology, Dalian Medical University, Dalian 116044, China.
Dalian Medical University · CNSecond Affiliated Hospital of Dalian Medical University · CNFirst Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCarbon TetrachlorideCells, CulturedDisease Models, AnimalGene Knockdown TechniquesHepatic Stellate CellsInflammasomesLiver CirrhosisMiceMitochondriaNLR Family, Pyrin Domain-Containing 3 ProteinReactive Oxygen SpeciesSrc Homology 2 Domain-Containing, Transforming Protein 1Carbon TetrachlorideInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseReactive Oxygen SpeciesShc1 protein, mouseSrc Homology 2 Domain-Containing, Transforming Protein 1hepatic stellate cellliver fibrosismitochondrial reactive oxygen speciesNLRP3 inflammasomep66Shc

Identifiers

PMID30867846
PMCPMC6401497
OpenAlexW2916299460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.