Evidence map›Paper›PMID 30867831›Full record

ArticleTheranostics2019

Iron Oxide Nanoflowers @ CuS Hybrids for Cancer Tri-Therapy: Interplay of Photothermal Therapy, Magnetic Hyperthermia and Photodynamic Therapy.

Alberto Curcio, Amanda K A Silva, Sonia Cabana, Ana Espinosa, Benoit Baptiste, Nicolas Menguy, Claire Wilhelm, Ali Abou-Hassan

Abstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

  1. Emerging copper-based hollow nanoplatforms for cancer treatment.International journal of pharmaceutics: X · 2026
    Review
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  7. Evaluation of CoFeInternational journal of molecular sciences · 2025
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  9. Article
  10. Review
  11. Review
  12. Article
  13. Magnetic Hyperthermia in Glioblastoma Multiforme Treatment.International journal of molecular sciences · 2024
    Review
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  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alberto CurcioSorbonne Université, CNRS UMR 8234, Physicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), 4 place Jussieu, 75005 Paris, France.
Amanda K A SilvaLaboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Université Paris Diderot, 75205 Paris Cedex 13, France.
Sonia CabanaSorbonne Université, CNRS UMR 8234, Physicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), 4 place Jussieu, 75005 Paris, France.
Ana EspinosaLaboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Université Paris Diderot, 75205 Paris Cedex 13, France.
Benoit BaptisteSorbonne Université, MNHN, CNRS UMR 7590, IRD - Institut de Minéralogie de Physique des Matériaux et de Cosmochimie (IMPMC), 4 place Jussieu, 75005 Paris, France.
Nicolas MenguySorbonne Université, MNHN, CNRS UMR 7590, IRD - Institut de Minéralogie de Physique des Matériaux et de Cosmochimie (IMPMC), 4 place Jussieu, 75005 Paris, France.
Claire WilhelmLaboratoire Matière et Systèmes Complexes, CNRS UMR 7057, Université Paris Diderot, 75205 Paris Cedex 13, France.
Ali Abou-HassanSorbonne Université, CNRS UMR 8234, Physicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), 4 place Jussieu, 75005 Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innovative synthesis routes revolutionized nanomaterial combination and design possibilities resulting in a new generation of fine-tuned nanoparticles featuring exquisite shape and constitution control. However, there is still room for improvement when it comes to the development of multi-functional nanoparticle agents merging a plurality of therapeutic functions to tackle tumors simultaneously by synergic mechanisms. Herein, we report the design of an optimized nanohybrid for cancer tri-therapy featuring a maghemite (γ-Fe2O3) nanoflower-like multicore nanoparticle conceived for efficient magnetic hyperthermia (MHT) and a spiky copper sulfide shell (IONF@CuS) with a high near-infrared (NIR) absorption coefficient suitable for photothermal (PTT) and photodynamic therapy (PDT).

Indexed as

AnimalsAntineoplastic AgentsCell Line, TumorCell SurvivalCopperFerric CompoundsHyperthermia, InducedMagnetic Field TherapyMice, NudeNanocompositesNeoplasmsPhotochemotherapyPhotosensitizing AgentsTreatment OutcomeXenograft Model Antitumor AssaysAntineoplastic AgentsCoppercupric sulfideFerric Compoundsferric oxidePhotosensitizing Agentscopper sulfideiron oxidemagnetic hyperthermiaphotodynamic therapyphotothermal therapy

Identifiers

PMID30867831
PMCPMC6401506

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.