Evidence map›Paper›PMID 30867822›Full record

ArticleTheranostics2019

Activated platelets in the tumor microenvironment for targeting of antibody-drug conjugates to tumors and metastases.

May Lin Yap, James D McFadyen, Xiaowei Wang, Melanie Ziegler, Yung-Chih Chen, Abbey Willcox, Cameron J Nowell, Andrew M Scott, Erica K Sloan, P Mark Hogarth and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Engineering platelets as cancer therapeutics.Nature reviews. Clinical oncology · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Natural carrier systems in cancer vaccines and immunotherapy.Human vaccines & immunotherapeutics · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

May Lin YapBaker Heart and Diabetes Institute, Melbourne, 3004, Australia.
James D McFadyenBaker Heart and Diabetes Institute, Melbourne, 3004, Australia.
Xiaowei WangBaker Heart and Diabetes Institute, Melbourne, 3004, Australia.
Melanie ZieglerBaker Heart and Diabetes Institute, Melbourne, 3004, Australia.
Yung-Chih ChenBaker Heart and Diabetes Institute, Melbourne, 3004, Australia.
Abbey WillcoxBaker Heart and Diabetes Institute, Melbourne, 3004, Australia.
Cameron J NowellDrug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
Andrew M ScottOlivia Newton-John Cancer Research Institute, and School of Cancer Medicine, La Trobe University, Melbourne, Victoria, Australia.
Erica K SloanDrug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
P Mark HogarthDepartment of Clinical Pathology, The University of Melbourne, Melbourne, 3010, Australia.
Geoffrey A PieterszBaker Heart and Diabetes Institute, Melbourne, 3004, Australia.
Karlheinz PeterBaker Heart and Diabetes Institute, Melbourne, 3004, Australia.
Baker Heart and Diabetes Institute · AUMonash University · AUBurnet Institute · AUOlivia Newton-John Cancer Wellness & Research Centre · AUUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Tumor MicroenvironmentAnimalsAntineoplastic AgentsBlood PlateletsDisease Models, AnimalImmunoconjugatesMiceMolecular Targeted TherapyNeoplasm MetastasisNeoplasm TransplantationOligopeptidesPlatelet Glycoprotein GPIb-IX ComplexPlatelet Glycoprotein GPIIb-IIIa ComplexSingle-Chain AntibodiesTransplantation, HeterologousTreatment OutcomeAntineoplastic Agentsglycoprotein receptor GPIb-IXImmunoconjugatesmonomethyl auristatin EOligopeptidesPlatelet Glycoprotein GPIb-IX ComplexPlatelet Glycoprotein GPIIb-IIIa ComplexSingle-Chain AntibodiesActivated plateletsAntibody-drug conjugateCancerGPIIb/IIIa

Identifiers

PMID30867822
PMCPMC6401411
OpenAlexW2911746982

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.