Evidence map›Paper›PMID 30867814›Full record

ArticleTheranostics2019

Human parthenogenetic neural stem cell grafts promote multiple regenerative processes in a traumatic brain injury model.

Jea-Young Lee, Sandra Acosta, Julian P Tuazon, Kaya Xu, Hung Nguyen, Trenton Lippert, Michael G Liska, Andrey Semechkin, Ibon Garitaonandia, Rodolfo Gonzalez and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jea-Young LeeCenter of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.
Sandra AcostaCenter of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.
Julian P TuazonCenter of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.
Kaya XuCenter of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.
Hung NguyenCenter of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.
Trenton LippertCenter of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.
Michael G LiskaCenter of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.
Andrey SemechkinInternational Stem Cell Corporation, Carlsbad, CA.
Ibon GaritaonandiaInternational Stem Cell Corporation, Carlsbad, CA.
Rodolfo GonzalezInternational Stem Cell Corporation, Carlsbad, CA.
Russell KernInternational Stem Cell Corporation, Carlsbad, CA.
Cesario V BorlonganCenter of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.
University of South Florida · USLineage Cell Therapeutics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

International Stem Cell Corporation human parthenogenetic neural stem cells (ISC-hpNSC) have potential therapeutic value for patients suffering from traumatic brain injury (TBI). Here, we demonstrate the behavioral and histological effects of transplanting ISC-hpNSC intracerebrally in an animal model of TBI.

Indexed as

Brain RegenerationAnimalsBrain Injuries, TraumaticCognitionDisease Models, AnimalHumansLocomotionNeural Stem CellsRats, Sprague-DawleyStem Cell TransplantationTreatment Outcomehuman parthenogenetic neural stem cellsinflammationneuroprotectionstem cell transplantationtraumatic brain injury

Identifiers

PMID30867814
PMCPMC6401413
OpenAlexW2914374917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.