Evidence map›Paper›PMID 30867748›Full record

ArticleOncology letters2019

Differential effects of ginkgol C17:1 on cisplatin-induced cytotoxicity: Protecting human normal L02 hepatocytes versus sensitizing human hepatoma HepG2 cells.

Yueying Li, Xinchi Zhang, Xiaoming Yang, Jun Liu, Linjie Li, Wenbin Ma, Min Chen

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Role of autophagy in alcohol and drug-induced liver injury.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yueying LiDepartment of Physiology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Xinchi ZhangDepartment of Immunology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Xiaoming YangDepartment of Food Science and Engineering, School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Jun LiuDepartment of Biology, Institute of Life Science, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Linjie LiSchool of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Wenbin MaSchool of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Min ChenDepartment of Physiology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Jiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver cancer is a major healthcare problem and one of the leading causes of cancer-associated mortality in the world. To date, chemotherapy remains a common method for treating cancer and cisplatin is one of the most widely used chemotherapeutics. However, owing to drug resistance and side effects, it is imperative to identify a novel approach to improve the anticancer effect of cisplatin. Auxiliary chemotherapy drugs with minor toxicity to normal cells may represent a novel strategy for cancer therapy. Previous studies have indicated that ginkgol C17:1 exhibits anticancer effects in liver cancer cells

Indexed as

cisplatinco-treatmentginkgol C17:1HepG2 cellsL02 cells

Identifiers

PMID30867748
PMCPMC6396107
OpenAlexW2914089065

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.