Evidence map›Paper›PMID 30867745›Full record

ArticleOncology letters2019

Induction of entosis in prostate cancer cells by nintedanib and its therapeutic implications.

Junjiang Liu, Lei Wang, Yunxia Zhang, Shoubin Li, Fuzhen Sun, Gang Wang, Tao Yang, Dong Wei, Liuxiong Guo, Helong Xiao

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Review
  7. Review
  8. Entosis in Health and Disease.Advances in experimental medicine and biology · 2025
    Review
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Junjiang LiuDepartment of Urology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Lei WangDepartment of Urology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, P.R. China.
Yunxia ZhangDepartment of Obstetrics and Gynecology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Shoubin LiDepartment of Urology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Fuzhen SunDepartment of Urology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Gang WangDepartment of Urology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Tao YangDepartment of Urology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Dong WeiDepartment of Urology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Liuxiong GuoDepartment of Urology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Helong XiaoDepartment of Urology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China.
Hebei General Hospital · CNFirst Affiliated Hospital of Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Entosis is a homogeneous cell-in-cell phenomenon and a non-apoptotic cell death process. Tyrosine kinase inhibitors have been used in the treatment of prostate cancer and have already demonstrated efficacy in a clinical setting. The present study investigated the role of entosis in prostate cancer treated with the tyrosine kinase inhibitor nintedanib. Prostate cancer cells were treated with nintedanib

Indexed as

cell division cycle 42entosisnintedanibphosphoinositide 3-kinaseprostate cancer

Identifiers

PMID30867745
PMCPMC6396220
OpenAlexW2910385463

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.