Evidence map›Paper›PMID 30867739›Full record

ArticleOncology letters2019

Experimental and clinicopathological analysis of HOXB9 in gastric cancer.

Fumihiko Kato, Norihito Wada, Tetsu Hayashida, Kazumasa Fukuda, Rieko Nakamura, Tsunehiro Takahashi, Hirofumi Kawakubo, Hiroya Takeuchi, Yuko Kitagawa

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Lymphangiogenesis in gastric cancer: function and mechanism.European journal of medical research · 2023
    Review
  6. Article
  7. Review
  8. Recent Multiomics Approaches in Endometrial Cancer.International journal of molecular sciences · 2022
    Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Fumihiko KatoDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Norihito WadaDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Tetsu HayashidaDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Kazumasa FukudaDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Rieko NakamuraDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Tsunehiro TakahashiDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Hirofumi KawakuboDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Hiroya TakeuchiDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Yuko KitagawaDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between homeobox (HOX)B9 expression and tumor malignancy was identified recently. It was reported that HOXB9 induced tumor angiogenesis, and associated with poor prognosis in patients with breast and colon cancer. On the other hand, regional lymph nodes are the most common site of tumor spread, and lymph node metastasis is a major prognostic factor in gastric cancer. It was hypothesized that HOXB9 promotes tumor lymphangiogenesis and induces tumor progression, invasion and metastasis in gastric cancer. The aim of the present study was to evaluate the correlation between HOXB9 expression, prognosis and clinicopathologic factors in patients with gastric cancer, and to assess the contribution of HOXB9 expression to tumor cell lymphangiogenesis

Indexed as

angiogenesisbiomarkerlymphangiogenesisTMK-1vascular endothelial growth factor-Cvascular endothelial growth factor-Dvascular endothelial growth factor receptor-3

Identifiers

PMID30867739
PMCPMC6396214
OpenAlexW2914625572

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.