ArticleExperimental and therapeutic medicine2019
Differential composition of gut microbiota among healthy volunteers, morbidly obese patients and post-bariatric surgery patients.
Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of bariatric surgery on gut microbiota in obese patients: A systematic review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Pooled it
- Gut Microbiota, Probiotics and Psychological States and Behaviors after Bariatric Surgery-A Systematic Review of Their Interrelation.Nutrients · 2020Pooled it
- Diet- and sex-related changes of gut microbiota composition and functional profiles after 4 months of weight loss intervention.European journal of nutrition · 2021Trial
- Changes in energy homeostasis, gut peptides, and gut microbiota in Emiratis with obesity after bariatric surgery.PloS one · 2025Article
- Human intestinal microbiome: Role in health and disease.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024Review
- Impact of Sleeve Gastrectomy on Fecal Microbiota in Individuals with Morbid Obesity.Microorganisms · 2023Article
- Changes in the Gut Microbiota Composition and Their Relation to Dietary Intake After Bariatric Surgery.Obesity surgery · 2023Article
- Profiles and diagnostic value of intestinal microbiota in schizophrenia patients with metabolic syndrome.Frontiers in endocrinology · 2023Article
- A specific gut microbiota signature is associated with an enhanced GLP-1 and GLP-2 secretion and improved metabolic control in patients with type 2 diabetes after metabolic Roux-en-Y gastric bypass.Frontiers in endocrinology · 2023Article
- Personalized Approach for Obese Patients Undergoing Endoscopic Sleeve Gastroplasty.Journal of personalized medicine · 2021Review
- Shifts in gut microbiota and their metabolites induced by bariatric surgery. Impact of factors shaping gut microbiota on bariatric surgery outcomes.Reviews in endocrine & metabolic disorders · 2021Review
- Sinomenine hydrochloride ameliorates dextran sulfate sodium-induced colitis in mice by modulating the gut microbiota composition whilst suppressing the activation of the NLRP3 inflammasome.Experimental and therapeutic medicine · 2021Article
- Alterations of Gut Bacteria in Hirschsprung Disease and Hirschsprung-Associated Enterocolitis.Microorganisms · 2021Review
- The Gut/Lung Microbiome Axis in Obesity, Asthma, and Bariatric Surgery: A Literature Review.Obesity (Silver Spring, Md.) · 2021Review
- From obesity through gut microbiota to cardiovascular diseases: a dangerous journey.International journal of obesity supplements · 2020Review
- Gut Microbiota Profiles of Treated Metabolic Syndrome Patients and their Relationship with Metabolic Health.Scientific reports · 2020Article
- Review
- A 5-Year Follow-up in Children and Adolescents Undergoing One-Anastomosis Gastric Bypass (OAGB) at a European IFSO Excellence Center (EAC-BS).Obesity surgery · 2019Article
- Longitudinal changes of microbiome composition and microbial metabolomics after surgical weight loss in individuals with obesity.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019Article
- Obesity-Related Epigenetic Changes After Bariatric Surgery.Frontiers in endocrinology · 2019Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The modulation of the gut microbiota was recently deemed one of the mechanisms responsible for the excellent outcomes of bariatric surgery. However, to date, only few studies have assessed this, and they have high heterogeneity. In the present study, next-generation 16S ribosomal DNA amplicon sequencing was used to characterize the gut microbiota of healthy volunteers, as well as patients prior to and after sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB). Significant differences in α diversity, β diversity and species were identified between the different groups/time-points. The results demonstrated excellent outcomes of SG and RYGB. The β diversity was lower in healthy volunteers compared with that in morbidly obese patients with or without type 2 diabetes mellitus. At 3 months after SG, the α diversity was increased and the β diversity was decreased. The abundance of certain species changed significantly after SG and RYGB. It was also revealed that the abundance of certain microbes was significantly correlated with the body mass index, fasting blood glucose and glycosylated haemoglobin. It may be concluded that bariatric surgery may cause obvious alterations in the gut microbiota and compared with healthy volunteers and obese patients without bariatric surgery, the microbiota composition of post-bariatric surgery has unique characteristics. However, studies with a larger cohort and longer follow-up may be required to confirm these results.
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