ArticleTropical medicine and health2019
Concurrence of CareStart™ Malaria HRP2 RDT with microscopy in population screening for
Article in Tropical medicine and health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- High value of rapid diagnostic tests to diagnose malaria within children: A systematic review and meta-analysis.Journal of global health · 2020Pooled it
- Unmasking non-malarial mosquito-borne infections among febrile children in malaria-endemic regions of western Kenya.Scientific reports · 2026Article
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- Asymptomatic Malaria Cases andPathogens (Basel, Switzerland) · 2024Article
- The fight against malaria in Edo-North, Edo State, Nigeria: identifying risk factors for effective control.PeerJ · 2024Article
- Malaria parasite burden and heterogeneity of risk factors among Central African Republic refugees: a cross-sectional study in the Gado-Badzere refugee camp in Eastern Cameroon.Frontiers in tropical diseases · 2024Article
- Burden of mosquito-borne diseases across rural versus urban areas in Cameroon between 2002 and 2021: prospective for community-oriented vector management approaches.Parasites & vectors · 2023Review
- Article
- Malaria diagnostic update: From conventional to advanced method.Journal of clinical laboratory analysis · 2022Review
- Asymptomatic Malaria Infections in the Time of COVID-19 Pandemic: Experience from the Central African Republic.International journal of environmental research and public health · 2022Article
- Impact of Malaria Diagnostic Technologies on the Disease Burden in the Sub-Saharan Africa.Journal of tropical medicine · 2022Review
- Performance of highly sensitive and conventional rapid diagnostic tests for clinical and subclinical Plasmodium falciparum infections, and hrp2/3 deletion status in Burundi.PLOS global public health · 2022Article
- Asymptomatic and sub-microscopic Plasmodium falciparum infection in children in the Mount Cameroon area: a cross-sectional study on altitudinal influence, haematological parameters and risk factors.Malaria journal · 2021Article
- Urogenital schistosomiasis burden in school-aged children in Tiko, Cameroon: a cross-sectional study on prevalence, intensity, knowledge and risk factors.Tropical medicine and health · 2021Article
- Diagnostic Accuracy of CareStart™ Malaria HRP2 and SD Bioline Pf/PAN for Malaria in Febrile Outpatients in Varying Malaria Transmission Settings in Cameroon.Diagnostics (Basel, Switzerland) · 2021Article
- Insecticide-treated net ownership, utilization and knowledge of malaria in children residing in Batoke-Limbe, Mount Cameroon area: effect on malariometric and haematological indices.Malaria journal · 2021Article
- Laboratory Detection of Malaria Antigens: a Strong Tool for Malaria Research, Diagnosis, and Epidemiology.Clinical microbiology reviews · 2021Article
- Malaria Rapid Diagnostic Tests: Literary Review and Recommendation for a Quality Assurance, Quality Control Algorithm.Diagnostics (Basel, Switzerland) · 2021Review
- Prevalence of Asymptomatic Malaria Infections in Seemingly Healthy Children, the Rural Dzanga Sangha Region, Central African Republic.International journal of environmental research and public health · 2021Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMalaria remains a diagnostic challenge in many endemic communities. Although rapid diagnostic tests (RDTs) are presently widely used for malaria diagnosis, there is a dearth of information on post-marketing surveillance on its efficacy in Cameroon. The present study evaluated the performance characteristics of CareStart™ Malaria HRP2 (histidine-rich protein 2) antigen (Ag) RDT in diagnosing
methodsThe CareStart™ Malaria HRP2
resultsMicroscopically confirmed malaria parasite prevalence was 27.7%, and geometric mean density was 187 parasites/μL of blood (range 70-1162). Se, Sp, PPV, NPV and accuracy were 82.4, 76.6, 57.4, 91.9 and 78.2%, respectively. Sensitivity depended on parasitaemia and reached 96.1% at densities ≥ 200 parasites/μL of blood. The accuracy of malaria parasitaemia (as assessed by the area under the receiver operating characteristic curve) to predict malaria by RDT was 75.4% (95% CI 70.6-80.1). The agreement between microscopy and RDT was moderate (
conclusionThe overall concurrence of CareStart™ Malaria HRP2 pf Ag RDT with microscopy in the detection of
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