Evidence map›Paper›PMID 30867336›Full record

ArticleAging2019

Influence of metabolic syndrome on the relationship between fatty acids and the selected parameters in men with benign prostatic hyperplasia.

Katarzyna Grzesiak, Aleksandra Rył, Weronika Ratajczak, Ewa Stachowska, Iwona Rotter, Marcin Słojewski, Olimpia Sipak, Kinga Walczakiewicz, Maria Laszczyńska

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Katarzyna GrzesiakDepartment of Histology and Developmental Biology, Pomeranian Medical University, Szczecin 71-210, Poland.
Aleksandra RyłDepartment of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University, Szczecin 71-210, Poland.
Weronika RatajczakDepartment of Histology and Developmental Biology, Pomeranian Medical University, Szczecin 71-210, Poland.
Ewa StachowskaDepartment of Biochemistry and Human Nutrition, Pomeranian Medical University, Szczecin 71-460, Poland.
Iwona RotterDepartment of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University, Szczecin 71-210, Poland.
Marcin SłojewskiDepartment of Urology and Urological Oncology, Pomeranian Medical University, Szczecin 70-111, Poland.
Olimpia SipakDepartment of Obstetrics and Pathology of Pregnancy, Pomeranian Medical University, Szczecin 71-210, Poland.
Kinga WalczakiewiczDepartment of Histology and Developmental Biology, Pomeranian Medical University, Szczecin 71-210, Poland.
Maria LaszczyńskaDepartment of Histology and Developmental Biology, Pomeranian Medical University, Szczecin 71-210, Poland.
Pomeranian Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of our investigation was to analyze the relationship between the serum levels of fatty acids and their metabolites and the levels of the selected metabolic and hormonal parameters in patients with benign prostatic hyperplasia (BPH) with regard to concomitant metabolic syndrome (MetS). We determined serum concentrations of total (TT) and free testosterone (FT), insulin (I), dehydroepiandrosterone sulphate (DHEAS), luteinizing hormone and insulin-like growth factor 1 (IGF-1) and sex hormone-binding globulin (SHBG). Gas chromatography was performed. The patients differed in terms of hormone levels, but only the differences in SHBG and IGF-1 levels were statistically significant. Analysis of the levels of polysaturated fatty acids in BPH patients showed that MetS contributed to changes in the levels of these acids. We also analyzed the relationship between the levels of fatty acids and diagnostic parameters for MetS. Particular abnormalities were associated with single changes in the levels of fatty acids. In the diabetic patients, changes in the levels of pentadecanoic acid, heptadecanoic acid and cis-11-eicosenoic acid were demonstrated. Our findings indicate the necessity for further investigation concerning the levels of fatty acids and their impact on the development of MetS, as well as the course and clinical picture of BPH.

Indexed as

AgedAged, 80 and overDehydroepiandrosteroneFatty AcidsFemaleHumansInsulinInsulin-Like Growth Factor ILuteinizing HormoneMaleMetabolic SyndromeMiddle AgedProstatic HyperplasiaTestosteroneDehydroepiandrosteroneFatty AcidsInsulinInsulin-Like Growth Factor ILuteinizing HormoneTestosteronebenign prostatic hyperplasiafatty acidsmetabolic syndrome

Identifiers

PMID30867336
PMCPMC6428091
OpenAlexW2921466882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.