Evidence map›Paper›PMID 30867290›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Molecular basis of chromatin remodeling by Rhp26, a yeast CSB ortholog.

Wei Wang, Jun Xu, Oliver Limbo, Jia Fei, George A Kassavetis, Jenny Chong, James T Kadonaga, Paul Russell, Bing Li, Dong Wang

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Biophysics of Chromatin Remodeling.Annual review of biophysics · 2021
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wei WangDivision of Pharmaceutical Sciences, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093.
Jun XuDivision of Pharmaceutical Sciences, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093.
Oliver LimboDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037.ORCID 0000-0003-1686-1414
Jia FeiSection of Molecular Biology, University of California, San Diego, La Jolla, CA 92093.
George A KassavetisSection of Molecular Biology, University of California, San Diego, La Jolla, CA 92093.
Jenny ChongDivision of Pharmaceutical Sciences, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093.
James T KadonagaSection of Molecular Biology, University of California, San Diego, La Jolla, CA 92093.
Paul RussellDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037.
Bing LiDepartment of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, 200025 Shanghai, China bingli@shsmu.edu.cn dongwang@ucsd.edu.
Dong WangDivision of Pharmaceutical Sciences, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093; bingli@shsmu.edu.cn dongwang@ucsd.edu.ORCID 0000-0002-2829-1546

Funding

Mechanisms of Eukaryotic Gene RegulationR35GM118060 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI James T. Kadonaga · 2016 to 2026
$7.5M
Studies of the DNA damage checkpointsR01CA077325 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI RUSSELL, PAUL · 1998 to 2017
$7.1M
Studies of the DNA Replication CheckpointR01GM059447 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI RUSSELL, PAUL · 1999 to 2016
$6.0M
Molecular Mechanisms for DNA Damage Processing by Transcription MachineryR01GM102362 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WANG, DONG · 2013 to 2025
$5.6M
Mre11/Rad50 Structural Biology for DNA Damage ResponsesR01CA117638 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI RUSSELL, PAUL, TAINER, JOHN A. · 2005 to 2019
$5.6M
NCI NIH HHS R01 CA077325NCI NIH HHS R01 CA117638NIGMS NIH HHS R01 GM059447NIGMS NIH HHS R01 GM102362NIGMS NIH HHS R35 GM118060
6 · The paper itself

Abstract

CSB/ERCC6 belongs to an orphan subfamily of SWI2/SNF2-related chromatin remodelers and plays crucial roles in gene expression, DNA damage repair, and the maintenance of genome integrity. The molecular basis of chromatin remodeling by Cockayne syndrome B protein (CSB) is not well understood. Here we investigate the molecular mechanism of chromatin remodeling by Rhp26, a

Indexed as

Chromatin Assembly and DisassemblyChromatinDNA HelicasesDNA RepairEpitopesHistonesSchizosaccharomycesSchizosaccharomyces pombe ProteinsChromatinDNA HelicasesEpitopesHistonesRhp26 protein, S pombeSchizosaccharomyces pombe Proteinschromatin remodelingCockayne syndrome Bhistone tailnucleosome sliding and evictionSNF2-like family ATPase

Identifiers

PMID30867290
PMCPMC6442633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.