Evidence map›Paper›PMID 30867287›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

DNA·RNA triple helix formation can function as a

Zhuo Zhou, Keith E Giles, Gary Felsenfeld

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Translation-Promoting Effects of RNA Template Overhangs in the Absence of Ribosomes.Angewandte Chemie (International ed. in English) · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. A New Strategy to Investigate RNA:DNA Triplex Using Atomic Force Microscopy.International journal of molecular sciences · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zhuo ZhouLaboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.
Keith E GilesLaboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.
Gary FelsenfeldLaboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892; gary.felsenfeld@nih.gov.
National Institute of Diabetes and Digestive and Kidney Diseases · US

Funding

Regulation Of Erythroid Gene ExpressionZIADK011005 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI FELSENFELD, GARY · 2009 to 2021
$3.2M
Regulation Of Erythroid Gene ExpressionZ01DK011005 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI FELSENFELD, GARY · 2002 to 2008
$704k
Intramural NIH HHS Z01 DK011005
6 · The paper itself

Abstract

We have identified regulatory mechanisms in which an RNA transcript forms a DNA duplex·RNA triple helix with a gene or one of its regulatory elements, suggesting potential auto-regulatory mechanisms in vivo. We describe an interaction at the human

Indexed as

beta-GlobinsDNAGenetic LociHumansK562 CellsNucleic Acid ConformationRNARNA Polymerase IITranscription, Geneticbeta-GlobinsDNARNARNA Polymerase IIDNA·RNA triplexDNA·RNA triplex RNA-mediated gene expressionFAU genehuman globin genes

Identifiers

PMID30867287
PMCPMC6442552
OpenAlexW2921291120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.