Evidence map›Paper›PMID 30867017›Full record

ArticleTrials2019

The effect of manual therapy and exercise on age-related lung function: study protocol for a randomised controlled trial.

Roger Engel, Sandra Grace, Suzanne Broadbent

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Roger EngelDepartment of Chiropractic, Macquarie University, North Ryde, Sydney, NSW, 2109, Australia. roger.engel@mq.edu.au.ORCID http://orcid.org/0000-0001-6021-0497
Sandra GraceSchool of Health and Human Sciences, Southern Cross University, Lismore, Australia.
Suzanne BroadbentSchool of Health and Sports Sciences, University of the Sunshine Coast, Sippy Downs, Australia.
Macquarie University · AUSouthern Cross University · AUUniversity of the Sunshine Coast · AU

Funding

Osteopathy Australia Research GrantSouthern Cross University Seed Grant
6 · The paper itself

Abstract

backgroundAgeing is associated with a range of anatomical and physiological changes. Establishing whether a change is part of 'normal' ageing or the early signs of disease will affect management strategies. Progressive stiffening of the thoracic spine, decreasing chest wall compliance and declining lung function begin as early as 40 years of age. Administering an intervention such as manual therapy, which has the potential to mitigate age-related changes in the thoracic spine and chest wall, has the potential to improve thoracic compliance and lung function. The aims of this trial are to investigate whether manual therapy can mitigate the effects of age-related changes in lung function and whether there is a difference in effect between different forms of manual therapy.

methodsThe study design is a randomised controlled trial of 372 people with no history of respiratory disease between the ages of 50 and 65 years. The cohort will be divided into three equal groups. The first group will receive a simple 10-min treadmill walking program (Ex). The second group will receive joint mobilisation (MB) of the thoracic spine and ribs plus the same walking program (MB + Ex). The third group will receive joint manipulation (MT) of the thoracic spine and ribs plus the same walking program (MT + Ex). All interventions will be administered a total of six times over a 3-week period. The primary outcome measure is lung function: forced expiratory volume in the 1st second and forced vital capacity. The secondary outcome measures include chest wall expansion (tape measurements) and quality of life measurements (36-Item Short Form Health Survey). Outcome measurements will be taken by blinded assessors on four occasions over a 9-week period. Adverse event data will be gathered at the beginning of each intervention session. DISCUSSION: This randomised controlled trial is designed to investigate whether manual therapy can mitigate the effects of age-related changes in lung function and whether there is a difference in effect between different forms of manual therapy. This is the first fully powered trial designed to test this hypothesis on healthy males and females in this age range.

trial registrationAustralian New Zealand Clinical Trials Registry (ANZCTR), 12616001317482 . Registered on 20 September 2016.

Indexed as

AgingAgedAge FactorsAnthropometryAustraliaCombined Modality TherapyExercise TherapyFemaleForced Expiratory VolumeHealth StatusHumansLungMaleMiddle AgedMulticenter Studies as TopicMusculoskeletal ManipulationsAgeingExerciseLung functionManual therapyRandomised controlled trialSpinal manipulationSpinal mobilisationTrial protocol

Identifiers

PMID30867017
PMCPMC6417040
OpenAlexW2947342221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.