Observational studyJournal of orthopaedic surgery and research2019
High cure rate of periprosthetic hip joint infection with multidisciplinary team approach using standardized two-stage exchange.
Observational study in Journal of orthopaedic surgery and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Cure rate of infections is not an argument for spacer in two-stage revision arthroplasty of the hip.Archives of orthopaedic and trauma surgery · 2023Trial
- Preoperative predictors of spacer retention and mortality in two-stage revision for infected total hip arthroplasties: a single-center experience of 90 patients.Arthroplasty (London, England) · 2026Article
- Performance of established test methods for diagnosing chronic periprosthetic joint infections caused by low-virulence pathogens.Bone & joint research · 2025Article
- Performance of established test methods in diagnosing persistent infection at the second stage of a two-stage procedure for periprosthetic hip and knee infections.Bone & joint open · 2025Article
- [Clinical application of multidisciplinary team in the diagnosis and treatment of chronic refractory wounds].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025Article
- Mid- to Long-Term Outcomes of Two-Stage Revision Arthroplasty for Periprosthetic Joint Infection of the Shoulder.Journal of clinical medicine · 2025Article
- Predictors of outcome following two-stage revision total knee arthroplasty.Archives of orthopaedic and trauma surgery · 2024Article
- Local Antibiotic Infusion in Periprosthetic Joint Infection Following Total Hip Arthroplasty.Journal of clinical medicine · 2024Review
- Is there sufficient evidence to support the use of antibiotic holiday just before the second stage of an infected total hip or knee arthroplasty revision surgery?World journal of orthopedics · 2024Article
- Clinical evaluation of a new technique for custom-made spacers in septic two-stage revision of total hip arthroplasties.Archives of orthopaedic and trauma surgery · 2023Article
- Interval between two-stage exchanges: what is optimal and how do you know?Arthroplasty (London, England) · 2023Review
- Two-stage revision for periprosthetic joint infection in cemented total hip arthroplasty: an increased risk for failure?Archives of orthopaedic and trauma surgery · 2023Review
- Poor outcome after debridement and implant retention for acute hematogenous periprosthetic joint infection: a cohort study of 43 patients.Acta orthopaedica · 2023Article
- Which Patients with Chronic Periprosthetic Joint Infection Are Less Suitable to Successful Two Stage Exchange Arthroplasty Surgery? A Retrospective Clinical Trial.Clinics and practice · 2023Article
- Total hip arthroplasty for destructive septic arthritis of the hip using a two-stage protocol without spacer placement.Archives of orthopaedic and trauma surgery · 2023Article
- Is long time to reimplantation a risk factor for reinfection in two-stage revision for periprosthetic infection? A systematic review of the literature.Frontiers in surgery · 2023Review
- A Multi-Disciplinary Approach for the Management of Prosthetic Joint Infections: An Australian Perspective.Malaysian orthopaedic journal · 2022Article
- [Individual megaspacers in two-stage revision of infected total hip arthroplasty-clinical and functional results after 2 years : Individual metal-endoskeleton cement spacer (iMECS)].Orthopadie (Heidelberg, Germany) · 2022Article
- Diagnostic value of the CD 15 focus score in two-stage revision arthroplasty of periprosthetic joint infections : High specificity in diagnosing infect eradication.Zeitschrift fur Rheumatologie · 2022Article
- Extended Trochanteric Osteotomy with Intermediate Resection Arthroplasty Is Safe for Use in Two-Stage Revision Total Hip Arthroplasty for Infection.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTwo-stage exchange arthroplasty is still the preferred treatment choice for chronic PJI. However, the results remain unpredictable. We analyzed the treatment success of patients with an infected hip prosthesis, who were treated according to a standardized algorithm with a multidisciplinary team approach and evaluated with a strict definition of failure.
methodsIn this single-center prospective cohort study, all hip PJI episodes from March 2013 to May 2015 were included. Treatment failure was assessed according to the Delphi-based consensus definition. The Kaplan-Meier survival method was used to estimate the probability of infection-free survival. Patients were dichotomized into two groups depending on the number of previous septic revisions, duration of prosthesis-free interval, positive culture with difficult-to-treat microorganisms, microbiology at explantation, and microbiology at reimplantation.
resultsEighty-four patients with hip PJI were the subject of this study. The most common isolated microorganisms were coagulase-negative staphylococci (CNS) followed by Staphylococcus aureus and Propionibacterium. Almost half of the study cohort (46%) had at least one previous septic revision before admission. The Kaplan-Meier estimated infection-free survival after 3 years was 89.3% (95% CI, 80% to 94%) with 30 patients at risk. The mean follow-up was 33.1 months (range, 24-48 months) with successful treatment of PJI. There were no statistical differences in infect eradication rate among the dichotomized groups.
conclusionsHigh infect eradication rates were achieved in a challenging cohort using a standardized two-stage exchange supported by a multidisciplinary approach.
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