Evidence map›Paper›PMID 30866926›Full record

Trial reportBMC health services research2019

Patient predictors of health-seeking behaviour for persons coughing for more than two weeks in high-burden tuberculosis communities: the case of the Western Cape, South Africa.

Carmen Christian, Cobus Burger, Mareli Claassens, Virginia Bond, Ronelle Burger

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC health services research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Multidimensional Poverty and Implementation Reach of Household Contact Tracing for Tuberculosis in South Africa: Analysis of a Randomized Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Trial
  3. Article
  4. Article
  5. Observational
  6. Reflections on qualitative research: Lessons learned to ensure research integrity.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Time to care-seeking for TB symptoms.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Article
  11. Article
  12. Article
  13. Assessing Factors Associated with TB Awareness in Nepal: A National and Subnational Study.International journal of environmental research and public health · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Carmen ChristianDepartment of Economics, Stellenbosch University, Matieland, 7602, South Africa. 18797067@sun.ac.za.
Cobus BurgerDepartment of Economics, Stellenbosch University, Matieland, 7602, South Africa.
Mareli ClaassensDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Tygerberg, 7505, South Africa.
Virginia BondDepartment of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, 15-17 Tavistock Place, London, WC1H9SH, UK.
Ronelle BurgerDepartment of Economics, Stellenbosch University, Matieland, 7602, South Africa.
Stellenbosch University · ZAFaculty of Public Health · GB

Funding

Bill and Melinda Gates Foundation (US) 19790.01National Research Foundation CPRR150722129596National Research Foundation RCA13102556861National Research Foundation SDG160531166953
6 · The paper itself

Abstract

backgroundThis study aimed to analyse the patient predictors of health-seeking behaviour for persons coughing for more than 2 weeks to better understand this vulnerable and important population.

methodsThe study analysed data from a cohort study (SOCS - Secondary Outcome Cohort Study) embedded in a community randomised trial ZAMSTAR (Zambia and South Africa TB and AIDS Reduction Study) in eight high-burden TB communities in the Western Cape, South Africa. These datasets are unique as they contain TB-related data as well as data on health, health-seeking behaviour, lifestyle choices, employment, socio-economic status, education and stigma. We use uni- and multivariate logistic regressions to estimate the odds ratios of consulting for a cough (of more than 2 weeks duration) for a range of relevant patient predictors.

resultsThree hundred and forty persons consulted someone about their cough and this represents 37% of the 922 participants who reported coughing for more than 2 weeks. In the multivariate analysis, respondents of black ethnic origin (OR 1.99, 95% CI 1.28-3.12, P < 0.01), those with higher levels of education (OR 1.05 per year of education, 95% CI 1.00-1.10, P = 0.05), and older respondents (OR 1.02 per year, 95% CI 1.01-1.04, P < 0.01) had a higher likelihood of consulting for their chronic cough. Individuals who smoked (OR 0.63, 95% CI 0.45-0.88, P < 0.01) and those with higher levels of socio-economic status (OR 0.81, 95% CI 0.71-0.92, P < 0.01) were less likely to consult. We find no evidence of stigma playing a role in health-seeking decisions, but caution that this may be due to the difficulty of accurately and reliably capturing stigma due to, amongst other factors, social desirability bias.

conclusionsThe low levels of consultation for a cough of more than 2 weeks suggest that there are opportunities to improve case-finding. These findings on health-seeking behaviour can assist policymakers in designing TB screening and active case-finding interventions that are targeted to the characteristics of those with a chronic cough who do not seek care.

Indexed as

Social StigmaAdultChronic DiseaseCoughEpidemiologic MethodsFemaleHealth BehaviorHumansMalePatient Acceptance of Health CareSex DistributionSocial ClassSouth AfricaTime-to-TreatmentTuberculosisVulnerable PopulationsChronic coughConsultingDelayed health seeking behaviourPresumptive TB

Identifiers

PMID30866926
PMCPMC6417175
OpenAlexW2921612897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.