ArticleAsian spine journal2019
Multifidus Muscles Lipid Content Is Associated with Intervertebral Disc Degeneration: A Quantitative Magnetic Resonance Imaging Study.
Article in Asian spine journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Imaging Evaluation of Fat Infiltration in Paraspinal Muscles on MRI: A Systematic Review with a Focus on Methodology.Orthopaedic surgery · 2021Pooled it
- Dynamic Ultrasound Quantification of Acupuncture-Induced Multifidus Recovery in Lumbar Disc Herniation.Journal of pain research · 2025Article
- Spinal degeneration is associated with lumbar multifidus morphology in secondary care patients with low back or leg pain.Scientific reports · 2022Article
- Factors associated with low back pain in patients with lumbar spinal stenosis: a cross-sectional study.BMC musculoskeletal disorders · 2022Article
- Magnetic Resonance Spectroscopic Analysis of Multifidus Muscle Lipid Contents and Association with Nociceptive Pain in Chronic Low Back Pain.Asian spine journal · 2021Article
- Association between lumbar segmental mobility and intervertebral disc degeneration quantified by magnetic resonance imaging T2 mapping.North American Spine Society journal · 2021Article
- Is the Lipid Content of the Psoas Major Correlated with Chronic Low Back Pain and Spinopelvic Alignment? A Magnetic Resonance Spectroscopic Study.Asian spine journal · 2020Article
- Imaging diagnosis for intervertebral disc.JOR spine · 2020Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Study Design: Cross-sectional study. Purpose: To determine the association between fatty degeneration of the multifidus muscle (Mm) and intervertebral disc degeneration (IVDD) using quantitative magnetic resonance imaging (MRI). Overview of Literature: Few studies have reported on quantitative MRI analysis of the relation between the Mm and IVDD. Methods: The subjects with chronic low back pain comprised 45 patients (19 males, 26 females; mean age, 63.8±2.0 years; range, 41-79 years). We analyzed the intramyocellular lipids (IMCL) and extramyocellular lipids (EMCL) of the Mm using magnetic resonance spectroscopy. The T2 values of the anterior annulus fibrosus (AF), nucleus pulposus (NP), and posterior AF were evaluated using MRI T2 mapping. We compared the possible correlations of IMCL and EMCL of the Mm with the T2 values of anterior AF, NP, and posterior AF. Results: There was a significant negative correlation between IMCL and T2 values of the anterior AF (r=-0.65, p<0.01). There were no significant correlations between the IMCL and T2 values of NP (r=-0.16, p=0.30) and posterior AF (r=0.07, p=0.62). There were no significant correlations between the EMCL and T2 values of the anterior AF (r=-0.11, p=0.46), NP (r=0.15, p=0.32), and posterior AF (r=0.07, p=0.66). After adjustment for age and sex using multiple linear regression analysis, there was a significant negative correlation between the IMCL and T2 values of anterior AF (standardized partial regression coefficient=-0.65, p<0.01). Conclusions: The results indicated that IMCL of the Mm might be accompanied with anterior AF degeneration. Therapeutic exercises using IMCL of the Mm as evaluation index might have the potential to identify novel targets for the treatment and prevention of IVDD.
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