Evidence map›Paper›PMID 30866548›Full record

ArticleViruses2019

Inactivation and Removal of Chikungunya Virus and Mayaro Virus from Plasma-derived Medicinal Products.

Constanze Yue, Sebastian Teitz, Tomoyuki Miyabashi, Klaus Boller, Lia Laura Lewis-Ximenez, Sally A Baylis, Johannes Blümel

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  6. Energy Requirements for Loss of Viral Infectivity.Food and environmental virology · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Constanze YueDepartment of Virology, Paul-Ehrlich-Institut, 63225 Langen, Germany. Constanze.Yue@pei.de.
Sebastian TeitzAsahi Kasei, 51105 Cologne, Germany. s.teitz@akbio.eu.
Tomoyuki MiyabashiAsahi Kasei, 51105 Cologne, Germany. miyabayashi.tb@om.asahi-kasei.co.jp.
Klaus BollerDepartment of Virology, Paul-Ehrlich-Institut, 63225 Langen, Germany. Klaus.Boller@pei.de.
Lia Laura Lewis-XimenezInstituto Oswaldo Cruz, Fundaçăo Oswaldo Cruz, Rio de Janeiro, RJ 21040-900, Brazil. lialewis.fiocruz@gmail.com.
Sally A BaylisDepartment of Virology, Paul-Ehrlich-Institut, 63225 Langen, Germany. Sally.Baylis@pei.de.
Johannes BlümelDepartment of Virology, Paul-Ehrlich-Institut, 63225 Langen, Germany. Johannes.Bluemel@pei.de.
Paul Ehrlich Institut · DEAsahi Kasei (Germany) · DEFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChikungunya virus (CHIKV) and Mayaro virus (MAYV) are closely related members of the Semliki Forest complex within the genus

methodsIn this study, we investigated the reduction of MAYV and CHIKV by heat inactivation in various matrices, solvent/detergent treatment and nanofiltration.

resultsUnexpectedly, MAYV was significantly more resistant to heat and solvent/detergent treatment compared to CHIKV. However, being similar in size, both MAYV and CHIKV were removed below the detection limit by 35 nm virus filters.

conclusionsThe inactivation profiles of different

Indexed as

Hot TemperatureVirus InactivationAlphavirusAnimalsChikungunya FeverChikungunya virusChlorocebus aethiopsDetergentsFiltrationNanotechnologyPlasmaSolventsVero CellsDetergentsSolventsalphaviruseschikungunya virusheat treatmentinactivationMayaro virusnanofiltrationplasma-derived medicinal productsS/D treatmentvirus retentive filtration

Identifiers

PMID30866548
PMCPMC6466239
OpenAlexW2918856964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.