Evidence map›Paper›PMID 30866528›Full record

ArticleNutrients2019

Docosahexaenoic Acid Inhibits Proliferation of EoL-1 Leukemia Cells and Induces Cell Cycle Arrest and Cell Differentiation.

Kalliopi Moustaka, Eirini Maleskou, Andromachi Lambrianidou, Stelios Papadopoulos, Marilena E Lekka, Theoni Trangas, Eirini Kitsiouli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Effects of Omega-3 Fatty Acids on Immune Cells.International journal of molecular sciences · 2019
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kalliopi MoustakaLaboratory of Biochemistry, Department of Biological Applications & Technologies, University of Ioannina, 45110 Ioannina, Greece. kallia.moustaka@gmail.com.
Eirini MaleskouLaboratory of Biochemistry, Department of Biological Applications & Technologies, University of Ioannina, 45110 Ioannina, Greece. emaleskou1988@gmail.com.
Andromachi LambrianidouLaboratory of Biochemistry, Department of Biological Applications & Technologies, University of Ioannina, 45110 Ioannina, Greece. mahilabrianidou@hotmail.com.
Stelios PapadopoulosLaboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece. stelios_ppp@yahoo.com.
Marilena E LekkaLaboratory of Biochemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece. mlekka@uoi.gr.ORCID 0000-0001-8667-4927
Theoni TrangasLaboratory of Biochemistry, Department of Biological Applications & Technologies, University of Ioannina, 45110 Ioannina, Greece. ttrangas@cc.uoi.gr.
Eirini KitsiouliLaboratory of Biochemistry, Department of Biological Applications & Technologies, University of Ioannina, 45110 Ioannina, Greece. ekitsiouli@gmail.com.
University of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Τhe effect of docosahexaenoic acid (DHA, an omega-3 polyunsaturated fatty acid) upon the proliferation of EoL-1 (Eosinophilic leukemia) cell line was assessed, while additional cellular events during the antiproliferative action were recorded. DHA inhibited EoL-1 cells growth dose-dependently by inducing growth arrest at G0/1 phase of the cell cycle. After DHA addition to the cells, the expression of

Indexed as

Cell Cycle CheckpointsCell DifferentiationCell Line, TumorCell ProliferationDocosahexaenoic AcidsGene ExpressionGroup IV Phospholipases A2HumansLeukemiamRNA Cleavage and Polyadenylation FactorsOncogene Proteins, FusionPlatelet Membrane GlycoproteinsProto-Oncogene Proteins c-mycReceptor, Platelet-Derived Growth Factor alphaReceptors, G-Protein-CoupledDocosahexaenoic AcidsFIP1L1-PDGFRA fusion protein, humanGroup IV Phospholipases A2mRNA Cleavage and Polyadenylation FactorsMYC protein, humanOncogene Proteins, FusionPLA2G4A protein, humanplatelet activating factor receptorPlatelet Membrane GlycoproteinsProto-Oncogene Proteins c-mycReceptor, Platelet-Derived Growth Factor alphaReceptors, G-Protein-CoupleddifferentiationDocosahexaenoicEoL-1G0/1 cycle arrestMYCPLA2G4APTAFR

Identifiers

PMID30866528
PMCPMC6471786
OpenAlexW2918851354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.