Evidence map›Paper›PMID 30866491›Full record

ArticleNutrients2019

Maternal Flavonoids Intake Reverts Depression-Like Behaviour in Rat Female Offspring.

Ana Laura de la Garza, Miguel A Garza-Cuellar, Ivan A Silva-Hernandez, Robbi E Cardenas-Perez, Luis A Reyes-Castro, Elena Zambrano, Brenda Gonzalez-Hernandez, Lourdes Garza-Ocañas, Lizeth Fuentes-Mera, Alberto Camacho

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Maternal Supplementation withDiseases (Basel, Switzerland) · 2024
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  13. Methanolic Extract ofDrug design, development and therapy · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ana Laura de la GarzaCentro de Investigación en Nutrición y Salud Pública, Facultad de Salud Pública y Nutrición, Universidad Autonoma de Nuevo Leon, 64460 Monterrey, Mexico. ana.dlgarzah@uanl.mx.ORCID 0000-0002-6049-903X
Miguel A Garza-CuellarDepartment of Biochemistry, Facultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, 66455 Monterrey, Mexico. miguel_94.10@hotmail.com.ORCID 0000-0002-7841-2510
Ivan A Silva-HernandezDepartment of Biochemistry, Facultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, 66455 Monterrey, Mexico. ivan_blaze914@hotmail.com.
Robbi E Cardenas-PerezDepartment of Biochemistry, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, 64460 Monterrey, Mexico. robbielizac@gmail.com.
Luis A Reyes-CastroReproductive Biology Department, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran, 14080 Mexico City, Mexico. lafe_mat@hotmail.com.ORCID 0000-0003-0397-6810
Elena ZambranoReproductive Biology Department, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran, 14080 Mexico City, Mexico. zamgon@yahoo.com.mx.
Brenda Gonzalez-HernandezDepartment of Biochemistry, Facultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, 66455 Monterrey, Mexico. gonzalebrenda@yahoo.com.
Lourdes Garza-OcañasDepartment of Pharmacology, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, 64460 Monterrey, Mexico. ogarza@live.com.mx.
Lizeth Fuentes-MeraDepartment of Biochemistry, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, 64460 Monterrey, Mexico. lizeth46@hotmail.com.ORCID 0000-0002-2649-5369
Alberto CamachoDepartment of Biochemistry, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, 64460 Monterrey, Mexico. alberto.camachomr@uanl.edu.mx.ORCID 0000-0002-2588-9489
Universidad Autónoma de Nuevo León · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MX

Funding

Consejo Nacional de Ciencia y Tecnología 255317 and 261420
6 · The paper itself

Abstract

Maternal hypercaloric exposure during pregnancy and lactation is a risk factor for developing diseases associated with inflammation such as obesity, diabetes and, neurological diseases in the offspring. Neuroinflammation might modulate neuronal activation and flavonoids are dietary compounds that have been proven to exert anti-inflammatory properties. Thus, the aim of the present study is to evaluate the effect of maternal supplementation with flavonoids (kaempferol-3-

Indexed as

AnimalsAntidepressive AgentsBehavior, AnimalDepressionDietDisaccharidesDrug InteractionsFemaleFlavanonesFlavonoidsImipramineInflammationKaempferolsMaleMaternal Nutritional Physiological PhenomenaMonosaccharidesAntidepressive AgentsDisaccharidesFlavanonesFlavonoidsImipraminekaempferol-3-O-glucosideKaempferolsMonosaccharidesnarirutinProtein Serine-Threonine KinasesTbk1 protein, mousedepressioninflammationkaempferolnarirutinnutritional programming

Identifiers

PMID30866491
PMCPMC6470771
OpenAlexW2919800113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.