Evidence map›Paper›PMID 30866469›Full record

ArticleMetabolites2019

Defining Metabolic Rewiring in Lung Squamous Cell Carcinoma.

Rachel Paes de Araújo, Natália Bertoni, Ana L Seneda, Tainara F Felix, Márcio Carvalho, Keir E Lewis, Érica N Hasimoto, Manfred Beckmann, Sandra A Drigo, Patricia P Reis and 1 more

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Rachel Paes de AraújoAberystwyth University, Institute of Biological, Environmental and Rural Sciences (IBERS), Ceredigion SY23 3DA, UK. rap23@aber.ac.uk.
Natália BertoniSão Paulo State University (UNESP), Faculty of Medicine, Dept. of Surgery and Orthopedics, Botucatu 18618687, Brazil. bertoni.na@gmail.com.
Ana L SenedaSão Paulo State University (UNESP), Faculty of Medicine, Dept. of Surgery and Orthopedics, Botucatu 18618687, Brazil. anaseneda@gmail.com.
Tainara F FelixSão Paulo State University (UNESP), Faculty of Medicine, Dept. of Surgery and Orthopedics, Botucatu 18618687, Brazil. felix.tainara@gmail.com.
Márcio CarvalhoSão Paulo State University (UNESP), School of Veterinary Medicine and Animal Science, Dept. of Veterinary Clinic, Botucatu 18618687, Brazil. marcio.carvalho@unesp.br.
Keir E LewisClinical Research Centre, Prince Philip Hospital, Hywel Dda University Health Board, Wales SA14 8QF, UK. k.e.lewis@swansea.ac.uk.ORCID 0000-0001-9756-4723
Érica N HasimotoSão Paulo State University (UNESP), Faculty of Medicine, Dept. of Surgery and Orthopedics, Botucatu 18618687, Brazil. ericanh80@hotmail.com.ORCID 0000-0002-5509-0862
Manfred BeckmannAberystwyth University, Institute of Biological, Environmental and Rural Sciences (IBERS), Ceredigion SY23 3DA, UK. meb@aber.ac.uk.
Sandra A DrigoSão Paulo State University (UNESP), Faculty of Medicine, Dept. of Surgery and Orthopedics, Botucatu 18618687, Brazil. sandradrigo@gmail.com.
Patricia P ReisSão Paulo State University (UNESP), Faculty of Medicine, Dept. of Surgery and Orthopedics, Botucatu 18618687, Brazil. patricia.reis@unesp.br.ORCID 0000-0003-3775-3797
Luis A J MurAberystwyth University, Institute of Biological, Environmental and Rural Sciences (IBERS), Ceredigion SY23 3DA, UK. lum@aber.ac.uk.ORCID 0000-0002-0961-9817
Centro Universitário de João Pessoa · BRAberystwyth University · GBUniversidade Estadual Paulista (Unesp) · BRSwansea University · GB

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 206386/2014Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88881.190242/2018-01Fundação de Amparo à Pesquisa do Estado de São Paulo 16/50429-1
6 · The paper itself

Abstract

Metabolomics based on untargeted flow infusion electrospray ionization high-resolution mass spectrometry (FIE-HRMS) can provide a snap-shot of metabolism in living cells. Lung Squamous Cell Carcinoma (SCC) is one of the predominant subtypes of Non-Small Cell Lung Cancers (NSCLCs), which usually shows a poor prognosis. We analysed lung SCC samples and matched histologically normal lung tissues from eight patients. Metabolites were profiled by FIE-HRMS and assessed using

Indexed as

flow infusion electrospray ionization high resolution mass spectrometrylung squamous cell carcinomapathwaysuntargeted metabolites

Identifiers

PMID30866469
PMCPMC6468359
OpenAlexW2919606708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.