Evidence map›Paper›PMID 30866452›Full record

ArticleInternational journal of molecular sciences2019

Testis-Specific SEPT12 Expression Affects SUN Protein Localization and is Involved in Mammalian Spermiogenesis.

Chung-Hsin Yeh, Ya-Yun Wang, Shi-Kae Wee, Mei-Feng Chen, Han-Sun Chiang, Pao-Lin Kuo, Ying-Hung Lin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Genetic etiological spectrum of sperm morphological abnormalities.Journal of assisted reproduction and genetics · 2024
    Review
  4. Protamine 2 deficiency results in Septin 12 abnormalities.Frontiers in cell and developmental biology · 2024
    Article
  5. Article
  6. Review
  7. Sperm Differentiation: The Role of Trafficking of Proteins.International journal of molecular sciences · 2020
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chung-Hsin YehDivision of Urology, Department of Surgery, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan. M000732@ms.skh.org.tw.
Ya-Yun WangDepartment of Chemistry, Fu Jen Catholic University, New Taipei City 242, Taiwan. vic0009@gmail.com.
Shi-Kae WeeGraduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 242, Taiwan. shikae1017@gmail.com.
Mei-Feng ChenBone and Joint Research Center, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan. mfchen0@gmail.com.
Han-Sun ChiangSchool of Medicine, Fu Jen Catholic University, New Taipei City 242, Taiwan. 053824@mail.fju.edu.tw.
Pao-Lin KuoDepartment of Obstetrics and Gynecology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. paolink@mail.ncku.edu.tw.
Ying-Hung LinGraduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 242, Taiwan. 084952@mail.fju.edu.tw.ORCID 0000-0002-1574-1579
Fu Jen Catholic University · TWChang Gung Memorial Hospital · TWNational Cheng Kung University Hospital · TW

Funding

Ministry of Science and Technology of the Republic of China MOST 106-2320-B-030-003-MY3, MOST 105-2314-B -030-001-, MOST 104-2314-B-030-001-, and MOST 103-2314-B-030-002-Shin-Kong Wu Ho-Su Memorial Hospital 104-SKH-FJU-05
6 · The paper itself

Abstract

Male infertility is observed in approximately 50% of all couples with infertility. Intracytoplasmic sperm injection (ICSI), a conventional artificial reproductive technique for treating male infertility, may fail because of a severe low sperm count, immotile sperm, immature sperm, and sperm with structural defects and DNA damage. Our previous studies have revealed that mutations in the septin (SEPT)-coding gene

Indexed as

SpermatogenesisAnimalsCarrier ProteinsCell NucleusCells, CulturedGene Knockout TechniquesHumansLamin Type AMaleMiceMicroscopy, ConfocalNuclear ProteinsOrgan SpecificitySeptinsTeratozoospermiaTestisCarrier ProteinsLamin Type ANuclear ProteinsSEPT12 protein, mouseSEPTIN12 protein, humanSeptinsSPAG4 protein, humanSUN4 protein, mouseSEPT12SPAG4spermiogenesis

Identifiers

PMID30866452
PMCPMC6429073
OpenAlexW2920348396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.