ArticlePloS one2019
Development and validation of DSM-5 based diagnostic tool for children with Autism Spectrum Disorder.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Screening and diagnostic tools for autism spectrum disorder: Systematic review and meta-analysis.Clinics (Sao Paulo, Brazil) · 2024Pooled it
- Effect of L-Carnosine as adjunctive therapy in the management of children with autism spectrum disorder: a randomized controlled study.Amino acids · 2020Trial
- Screening children and adolescents with mild to moderate intellectual disability for autistic symptoms with the Indian Autism Screening Questionnaire (IASQ).Indian journal of psychiatry · 2026Article
- Elemental and Isotopic Profiles in Blood and Urine of Jordanian Children with Autism Spectrum Disorder: a Preliminary Comparative Study with Neurotypical Children.Biological trace element research · 2026Article
- Association of iron deficiency and iron-deficiency anemia with behavioral problems in children with autism: a cross-sectional study.Frontiers in psychiatry · 2026Article
- Assessment of psychometric properties of autism spectrum diagnostic profile (ASDP) among Egyptian children aged 2-12 years.BMC psychiatry · 2025Article
- Whole Exome Sequencing of a Multiplex Family of Indian Origin Identifies Variants in theMolecular syndromology · 2024Article
- Using mobile health technology to assess childhood autism in low-resource community settings in India: An innovation to address the detection gap.Autism : the international journal of research and practice · 2024Article
- Early Diagnosis of Autism Spectrum Disorder: What the Pediatricians Should Know.Indian journal of pediatrics · 2023Review
- Autism in India: Time for a national programme.The Indian journal of medical research · 2023Article
- Adequate Management of Autism Spectrum Disorder in Children in India.Indian journal of pediatrics · 2023Review
- Caregiver Perceptions of Autism and Neurodevelopmental Disabilities in New Delhi, India.International journal of environmental research and public health · 2023Article
- Individually tailored dosage regimen of full-spectrum Cannabis extracts for autistic core and comorbid symptoms: a real-life report of multi-symptomatic benefits.Frontiers in psychiatry · 2023Article
- Article
- Video-based screening for children with suspected autism spectrum disorder - experience during the COVID-19 pandemic in India.Research in autism spectrum disorders · 2022Article
- mHealth apps delivering early intervention to support parents of children with autism: a scoping review protocol.BMJ paediatrics open · 2022Article
- Early Interventions for Infants at Risk for Developmental Impairment: The South Asian Perspective.Indian journal of pediatrics · 2022Review
- The Route to Autism Spectrum Diagnosis in Pediatric Practice in Bulgaria.Diagnostics (Basel, Switzerland) · 2021Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diagnostic and Statistical Manual of mental disorder-IV (DSM-IV) TR based INCLEN Diagnostic Tool for Autism Spectrum Disorder (INDT-ASD) is an established instrument for the diagnosis of ASD in Indian subcontinent and low-middle income countries (LMIC). The introduction of DSM-5 necessitated revision of existing INDT-ASD tool to incorporate the DSM-5 related changes. This study was undertaken to develop and validate the DSM-5 based All India Institute of Medical Sciences (AIIMS)-Modified-INDT-ASD Tool. The modifications were done using Delphi method and included: (a) rearrangement of questions from the previous tool; and (b) addition of new questions on sensory symptoms. The modified tool was validated against DSM-5 diagnostic criteria. In addition, receiver operating characteristic (ROC) curves were used to determine the cut-off for total score as compared to Childhood Autism Rating Scale (CARS) score to grade the severity of ASD. Two-hundred-twenty-five children (159 boys, median age = 47months) were enrolled. The modified tool demonstrated sensitivity of 98.4% and specificity of 91.7% to diagnose ASD. A score ≥14 on the tool was suggestive of severe ASD (CARS>36.5) with a sensitivity and specificity of 80% and 80.7% respectively [Area under the curve = 0.89]. AIIMS-Modified-INDT-ASD Tool is a simple and structured instrument based on DSM-5 criteria which can facilitate diagnosis of ASD with acceptable diagnostic accuracy.
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