ArticlePloS one2019
Comparative evaluation of three dengue duo rapid test kits to detect NS1, IgM, and IgG associated with acute dengue in children in Myanmar.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Diagnostic performance of the Dengue NS1 Ag Rapid Test during early-stage infections at epidemic-affected health care facilities in northeastern and eastern Ethiopia.IJID regions · 2026Article
- Combined Analytical and Clinical Performance Evaluation of a Novel Dengue NS1 Rapid Test in a Real-World Endemic Setting.Diagnostics (Basel, Switzerland) · 2026Article
- Dengue virus infection amongst malaria and typhoid fever suspected acute febrile patients in the Niger river basin of Nigeria.Scientific reports · 2025Article
- Neglected and lethal: Case series of fatal scrub typhus in Malaysia.PLoS neglected tropical diseases · 2025Article
- Review
- Laboratory Evaluation and Field Testing of Dengue NS1 and IgM/IgG Rapid Diagnostic Tests in an Epidemic Context in Senegal.Viruses · 2023Article
- Diagnostic Performance of Dengue NS1 and Antibodies by Serum Concentration Technique.Tropical medicine and infectious disease · 2023Article
- Diagnostic Accuracy of Various Immunochromatographic Tests for NS1 Antigen and IgM Antibodies Detection in Acute Dengue Virus Infection.International journal of environmental research and public health · 2022Article
- Assessment of dengue virus threat to blood safety and community health: A single center study in northern Egypt.Journal of virus eradication · 2022Article
- Combining rapid diagnostic tests to estimate primary and post-primary dengue immune status at the point of care.PLoS neglected tropical diseases · 2022Article
- Prospective Evaluation of a Commercial Dengue NS1 Antigen Rapid Diagnostic Test in New Caledonia.Microorganisms · 2022Article
- Article
- Immuno-dominant dengue NS1 peptides as antigens for production of monoclonal antibodies.Frontiers in molecular biosciences · 2022Article
- Clinical and epidemiologic characteristics associated with dengue fever in 2011-2016 in Bang Phae district, Ratchaburi province, Thailand.PLoS neglected tropical diseases · 2021Article
- Application of One-Step Reverse Transcription Droplet Digital PCR for Dengue Virus Detection and Quantification in Clinical Specimens.Diagnostics (Basel, Switzerland) · 2021Article
- Dengue pre-vaccination screening test evaluation for the use of dengue vaccine in an endemic area.PloS one · 2021Article
- Evaluation of eight commercial Zika virus IgM and IgG serology assays for diagnostics and research.PloS one · 2021Article
- Diagnostic Performance of Dengue Virus Envelope Domain III in Acute Dengue Infection.International journal of molecular sciences · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dengue is an increasing public health concern worldwide and requires efficient laboratory diagnostics. We evaluated three commercially available dengue rapid diagnostic tests-the Humasis Dengue Combo NS1 & IgG/IgM (Humasis, Korea), SD Bioline Dengue Duo NS1 Ag & IgG/IgM (SD Bioline, Korea), and CareUS Dengue Combo NS1 and IgM/IgG kits (WellsBio, Korea)-and compared them to reference immunoglobulin M (IgM) or immunoglobulin G (IgG) ELISAs and quantitative reverse transcription polymerase chain reaction (qRT-PCR) assays. In total, 109 dengue-positive samples from children with acute symptomatic dengue and 63 dengue-negative samples from febrile and asymptomatic individuals were collected. For the nonstructural 1 protein (NS1) Ag test, the sensitivity and specificity were in the following order: CareUS (79.82 and 100%), Humasis (63.30 and 100%), and SD Bioline (48.62 and 100%). For IgM and IgG, CareUS had the highest sensitivities and specificities (89.91 and 100%; 82.57 and 100%, respectively), followed by SD Bioline (60.55 and 100%, 77.98 and 100%, respectively), and Humasis (51.38 and 98.21%, 72.48 and 95.24%, respectively). The IgM kits were more sensitive than the NS1 Ag or IgG kits; however, combining NS1 Ag and IgM reduced the number of missed cases. Therefore, the NS1 Ag plus IgM dengue kits increase the accuracy of the results. In our study, the CareUS Dengue Combo NS1 and IgM/IgG kit showed higher accuracy in performance with reference to qRT-PCR and ELISA results.
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