Evidence map›Paper›PMID 30865648›Full record

ArticlePloS one2019

Sucrose and starch intake contribute to reduced alveolar bone height in a rodent model of naturally occurring periodontitis.

Juliano Morimoto, Alistair Senior, Kate Ruiz, Jibran A Wali, Tamara Pulpitel, Samantha M Solon-Biet, Victoria C Cogger, David Raubenheimer, David G Le Couteur, Stephen J Simpson and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Juliano MorimotoCharles Perkins Centre, Camperdown, New South Wales, Australia.
Alistair SeniorCharles Perkins Centre, Camperdown, New South Wales, Australia.
Kate RuizCharles Perkins Centre, Camperdown, New South Wales, Australia.
Jibran A WaliCharles Perkins Centre, Camperdown, New South Wales, Australia.
Tamara PulpitelCharles Perkins Centre, Camperdown, New South Wales, Australia.
Samantha M Solon-BietCharles Perkins Centre, Camperdown, New South Wales, Australia.
Victoria C CoggerCharles Perkins Centre, Camperdown, New South Wales, Australia.
David RaubenheimerCharles Perkins Centre, Camperdown, New South Wales, Australia.
David G Le CouteurCharles Perkins Centre, Camperdown, New South Wales, Australia.
Stephen J SimpsonCharles Perkins Centre, Camperdown, New South Wales, Australia.
Joerg EberhardCharles Perkins Centre, Camperdown, New South Wales, Australia.ORCID 0000-0001-8060-2893
The University of Sydney · AUConcord Repatriation General Hospital · AUCooperative Trials Group for Neuro-Oncology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While there is a burgeoning interest in the effects of nutrition on systemic inflammatory diseases, how dietary macronutrient balance impacts local chronic inflammatory diseases in the mouth has been largely overlooked. Here, we used the Geometric Framework for Nutrition to test how the amounts of dietary macronutrients and their interactions, as well as carbohydrate type (starch vs sucrose vs resistant starch) influenced periodontitis-associated alveolar bone height in mice. Increasing intake of carbohydrates reduced alveolar bone height, while dietary protein had no effect. Whether carbohydrate came from sugar or starch did not influence the extent of alveolar bone height. In summary, the amount of carbohydrate in the diet modulated periodontitis-associated alveolar bone height independent of the source of carbohydrates.

Indexed as

Feeding BehaviorAlveolar Bone LossAlveolar ProcessAnimalsDietary ProteinsDietary SucroseDisease Models, AnimalHumansMaleMiceMice, Inbred C57BLOrgan SizePeriodontitisStarchDietary ProteinsDietary SucroseStarch

Identifiers

PMID30865648
PMCPMC6415785
OpenAlexW2922208425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.