Evidence map›Paper›PMID 30865358›Full record

ArticleHuman brain mapping2019

Neurochemical correlates of scene processing in the precuneus/posterior cingulate cortex: A multimodal fMRI and

Alison G Costigan, Katja Umla-Runge, C John Evans, Carl J Hodgetts, Andrew D Lawrence, Kim S Graham

Open access · hybridAbstract read
In one paragraph

Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Central Dysmyelination in SSADH-Deficient Humans and Mice.Annals of clinical and translational neurology · 2025
    Observational
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  9. Mind your step: social cerebellum in interactive navigation.Social cognitive and affective neuroscience · 2023
    Article
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  11. Regional specificity and clinical correlates of cortical GABA alterations in posttraumatic stress disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
  12. Article
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  15. The precuneal cortex: anatomy and seizure semiology.Epileptic disorders : international epilepsy journal with videotape · 2021
    Review
  16. Semantic Knowledge of Famous People and Places Is Represented in Hippocampus and Distinct Cortical Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alison G CostiganCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Wales, UK.
Katja Umla-RungeCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Wales, UK.
C John EvansCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Wales, UK.
Carl J HodgettsCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Wales, UK.
Andrew D LawrenceCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Wales, UK.
Kim S GrahamCardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Wales, UK.
Cardiff University · GB

Funding

Cardiff University Neuroscience and Mental Health Research InstituteMedical Research Council G1002149Medical Research Council MR/N01233X/1Wellcome TrustWellcome Trust 104943/Z/14/Z
6 · The paper itself

Abstract

Precuneus/posterior cingulate cortex (PCu/PCC) are key components of a midline network, activated during rest but also in tasks that involve construction of scene or situation models. Despite growing interest in PCu/PCC functional alterations in disease and disease risk, the underlying neurochemical modulators of PCu/PCC's task-evoked activity are largely unstudied. Here, a multimodal imaging approach was applied to investigate whether interindividual differences in PCu/PCC fMRI activity, elicited during perceptual discrimination of scene stimuli, were correlated with local brain metabolite levels, measured during resting-state

Indexed as

Brain MappingFemaleGyrus CinguliHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMultimodal ImagingVisual PerceptionYoung Adultdefault mode networkfMRI-MRSGABAglutamateN-acetyl aspartateposterior cingulate cortexprecuneusscene perception

Identifiers

PMID30865358
PMCPMC6563468
OpenAlexW2949886873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.