Evidence map›Paper›PMID 30865007›Full record

ReviewCurrent opinion in neurology2019

Management of neurosarcoidosis: a clinical challenge.

Mareye Voortman, Marjolein Drent, Robert P Baughman

Abstract readReview
In one paragraph

Review in Current opinion in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Rare Neurosarcoidosis Involvements.Respirology case reports · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Disparate Prednisone Starting Dosages for Systemic Corticosteroid-Naïve Veterans With Active Sarcoidosis.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025
    Article
  11. Article
  12. The pleomorphic phenotype of neurosarcoidosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Neurosarcoidosis: An under-diagnosed cause of myelopathy.Journal of family medicine and primary care · 2024
    Article
  17. Cardiac Involvement in Neurosarcoidosis: A Single-Center InvestigationNeurology(R) neuroimmunology & neuroinflammation · 2024
    Article
  18. Reevaluating the relevance ofNeurological research and practice · 2024
    Article
  19. A rare case of sarcoid myelitis complicating Löfgren's syndrome.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mareye VoortmanILD Center of Excellence, Department of Pulmonology, St. Antonius Hospital, Nieuwegein.
Marjolein DrentILD Center of Excellence, Department of Pulmonology, St. Antonius Hospital, Nieuwegein.
Robert P BaughmanDepartment of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewSarcoidosis is a complex disease with many faces, and the clinical manifestation and course of neurosarcoidosis are particularly variable. Although neurosarcoidosis occurs in up to 10% of sarcoidosis patients, it can lead to significant morbidity and some mortality. RECENT

findingsThree criteria are usually required for a diagnosis of (neuro)sarcoidosis: clinical and radiologic manifestations, noncaseating granulomas, and no evidence of alternative disease. Recent guidelines have helped to clarify criteria for diagnosing neurosarcoidosis. No firm guidelines exist on whether, when, and how treatment should be started. Treatment depends on the presentation and distribution, extensiveness, and severity of neurosarcoidosis. As regards evidence-based treatment, only a few randomized controlled trials have been done. Hence, several aspects of (neuro)sarcoidosis management are not fully addressed by the current literature. SUMMARY: Significant advances have been made in the potential and accuracy of diagnostics for neurosarcoidosis. Treatment should be approached within the context of the patient's anticipated clinical course, avoidance of adverse drug effects, and, if necessary, from the perspective of the comprehensive management of a chronic disease. A multidisciplinary approach to the management of sarcoidosis is strongly recommended.

Indexed as

Central Nervous System DiseasesDisease ManagementHumansPatient Care TeamSarcoidosis

Identifiers

PMID30865007
PMCPMC6522203

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.