ArticleeLife2019
Empirical examination of the replicability of associations between brain structure and psychological variables.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
95 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Shared neuroimaging and molecular profiles in type 2 diabetes mellitus and major depressive disorder: an integrative analysis of genetic, transcriptomic, and neuroimaging data.Translational psychiatry · 2025Pooled it
- Multivariate brain-behaviour associations in psychiatric disorders.Translational psychiatry · 2024Pooled it
- Convergent abnormality in the subgenual anterior cingulate cortex in insomnia disorder: A revisited neuroimaging meta-analysis of 39 studies.Sleep medicine reviews · 2023Pooled it
- In search of convergent regional brain abnormality in cognitive emotion regulation: A transdiagnostic neuroimaging meta-analysis.Human brain mapping · 2022Pooled it
- Structural and functional neuroimaging of late-life depression: a coordinate-based meta-analysis.Brain imaging and behavior · 2022Pooled it
- Balancing act: Neural correlates of affect dysregulation in youth depression and substance use - A systematic review of functional neuroimaging studies.Developmental cognitive neuroscience · 2020Pooled it
- Trial
- Loneliness relates to smaller hippocampal subfield volumes in individuals with elevated plasma pTau217: results from IGNITE.GeroScience · 2026Article
- Garbage in, garbage out: stringent quality control of behavioral data boosts signal in brain-behavior associations.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Bias in Structural MRI Correlates of Delay Discounting due to Head Motion.Human brain mapping · 2026Article
- MIND versus MSN: A systematic evaluation of test-retest reliability and age sensitivity for T1-weighted structural similarity networks.Network neuroscience (Cambridge, Mass.) · 2026Article
- Lasting effects of oral contraceptives on fear responses to a safe context.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Impact of Technological Immersion and Sensorimotor Engagement on Performance and Brain Plasticity in Short-Term Second Language Vocabulary Training.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Association between neuroticism and brain-wide structural outcomes: Mediation by vascular and mental conditions.Psychological medicine · 2025Article
- Effects of cortical thickness, volume, and memory performance on age differences in neural reinstatement of scene information.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Genetic contributions to brain criticality and its relationship with human cognitive functions.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Longer scans boost prediction and cut costs in brain-wide association studies.bioRxiv : the preprint server for biology · 2025Article
- How to Produce, Identify, and Motivate Robust Psychological Science: A Roadmap and a Response to Vize et al.Assessment · 2025Article
- Bias in data-driven replicability analysis of univariate brain-wide association studies.Scientific reports · 2025Article
- Using precision approaches to improve brain-behavior prediction.Trends in cognitive sciences · 2025Review
35 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
Linking interindividual differences in psychological phenotype to variations in brain structure is an old dream for psychology and a crucial question for cognitive neurosciences. Yet, replicability of the previously-reported 'structural brain behavior' (SBB)-associations has been questioned, recently. Here, we conducted an empirical investigation, assessing replicability of SBB among heathy adults. For a wide range of psychological measures, the replicability of associations with gray matter volume was assessed. Our results revealed that among healthy individuals 1) finding an association between performance at standard psychological tests and brain morphology is relatively unlikely 2) significant associations, found using an exploratory approach, have overestimated effect sizes and 3) can hardly be replicated in an independent sample. After considering factors such as sample size and comparing our findings with more replicable SBB-associations in a clinical cohort and replicable associations between brain structure and non-psychological phenotype, we discuss the potential causes and consequences of these findings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.