Evidence map›Paper›PMID 30864607›Full record

ArticleJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia2019

Accuracy of a rapid molecular test for tuberculosis in sputum samples, bronchoalveolar lavage fluid, and tracheal aspirate obtained from patients with suspected pulmonary tuberculosis at a tertiary referral hospital.

Tatiane Maria da Silva, Valéria Martins Soares, Mariana Gontijo Ramos, Adriana Dos Santos

Open access · diamondAbstract readEditorial
In one paragraph

Article in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Role of GeneXpertTropical medicine and infectious disease · 2023
    Article
  8. Article
  9. Comparison of the diagnostic efficacy of the CapitalBio Mycobacterium real-time polymerase chain reaction detection test and Xpert MTB/RIF in smear-negative pulmonary tuberculosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  10. Tuberculosis series 2019.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tatiane Maria da Silva. Faculdade de Biomedicina, Universidade da Fundação Mineira de Educação e Cultura - FUMEC - Belo Horizonte (MG) Brasil.ORCID 0000-0002-5108-6006
Valéria Martins Soares. Setor de Microbiologia, Laboratório do Hospital Júlia Kubitschek, Fundação Hospitalar do Estado de Minas Gerais - FHEMIG - Belo Horizonte (MG) Brasil.ORCID 0000-0002-7976-0592
Mariana Gontijo Ramos. Faculdade de Biomedicina, Universidade da Fundação Mineira de Educação e Cultura - FUMEC - Belo Horizonte (MG) Brasil.ORCID 0000-0002-9232-7857
Adriana Dos Santos. Faculdade de Biomedicina, Universidade da Fundação Mineira de Educação e Cultura - FUMEC - Belo Horizonte (MG) Brasil.ORCID 0000-0001-8109-6777
Universidade Fundação Mineira de Educação e Cultura · BRFundação Hospitalar do Estado de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis continues to be a major public health problem worldwide. The aim of the present study was to evaluate the accuracy of the Xpert MTB/RIF rapid molecular test for tuberculosis, using pulmonary samples obtained from patients treated at the Júlia Kubitschek Hospital, which is operated by the Hospital Foundation of the State of Minas Gerais, in the city of Belo Horizonte, Brazil. This was a retrospective study comparing the Xpert MTB/RIF test results with those of standard culture for Mycobacterium tuberculosis and phenotypic susceptibility tests. Although the Xpert MTB/RIF test showed high accuracy for the detection of M. tuberculosis and its resistance to rifampin, attention must be given to the clinical status of the patient, in relation to the test results, as well as to the limitations of molecular tests.

Indexed as

Antibiotics, AntitubercularBronchoalveolar Lavage FluidDNA, BacterialDrug Resistance, BacterialHumansMolecular Diagnostic TechniquesMycobacterium tuberculosisNucleic Acid Amplification TechniquesReproducibility of ResultsRetrospective StudiesRifampinSensitivity and SpecificitySputumTertiary Care CentersTracheaTuberculosis, PulmonaryAntibiotics, AntitubercularDNA, BacterialRifampin

Identifiers

PMID30864607
PMCPMC6733743
OpenAlexW2920826509

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.