ArticlePharmacoEconomics2019
Measuring Health Spillover Effects in Caregivers of Children with Autism Spectrum Disorder: A Comparison of the EQ-5D-3L and SF-6D.
Article in PharmacoEconomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- The Psychometric Performance of Generic Preference-Based Measures in Informal Carers: A Systematic Review of Validation Studies.PharmacoEconomics · 2025Pooled it
- Outcome measures for economic evaluations and cost-effectiveness analyses of interventions for people with intellectual disabilities: A methodological systematic review.Journal of applied research in intellectual disabilities : JARID · 2023Pooled it
- Spillover Effects on Caregivers' and Family Members' Utility: A Systematic Review of the Literature.PharmacoEconomics · 2019Pooled it
- Sleeping Sound Autism Spectrum Disorder (ASD): Cost-Effectiveness of a Brief Behavioural Sleep Intervention in Primary School-Aged Autistic Children.Journal of autism and developmental disorders · 2025Trial
- Measuring and valuing spillover effects in caregivers and families: A scoping review.PloS one · 2026Article
- Caring for and Caring about in Economic Evaluation: Modelling the Family and Caregiving Effects.PharmacoEconomics · 2026Article
- EQ-5D-5L or EQ-HWB-S: Which is the Better Instrument for Capturing Spillover Effects in Parental Carers of Children with COVID-19?PharmacoEconomics · 2025Article
- The economic impact of caregiving for individuals with Angelman syndrome in the United States: results from a caregiver survey.Orphanet journal of rare diseases · 2025Article
- Assessing the psychometric performance of the EQ-5D-5L among informal caregivers of people with dementia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Comparative performance and mapping algorithms between EQ-5D-5L and SF-6Dv2 among the Chinese general population.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Article
- Research trends in contemporary health economics: a scientometric analysis on collective content of specialty journals.Health economics review · 2024Review
- Comparison of the measurement properties of SF-6Dv2 and EQ-5D-5L in a Chinese population health survey.Health and quality of life outcomes · 2022Article
- A Personalized Multidisciplinary Approach to Evaluating and Treating Autism Spectrum Disorder.Journal of personalized medicine · 2022Review
- Transdermal Electrical Neuromodulation for Anxiety and Sleep Problems in High-Functioning Autism Spectrum Disorder: Feasibility and Preliminary Findings.Journal of personalized medicine · 2021Article
- What's the Cost? Measuring the Economic Impact of Pediatric Sepsis.Frontiers in pediatrics · 2021Article
- Parental health spillover effects of paediatric rare genetic conditions.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Pediatric Concurrent Hospice Care: A Scoping Review and Directions for Future Nursing Research.Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association · 2020Article
- Emerging biomarkers in autism spectrum disorder: a systematic review.Annals of translational medicine · 2019Review
- Advances in Methods and Novel Applications for Measuring Family Spillover Effects of Illness.PharmacoEconomics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
BACKGROUND AND
objectiveHealthcare interventions that improve the health of children with autism spectrum disorder (ASD) have the potential to affect the health of caregivers. This study compares the three-level EuroQoL-5 Dimension (EQ-5D-3L) and the Short Form-6 Dimension (SF-6D) in their ability to value such spillover effects in caregivers.
methodsClinical data collected from two Autism Treatment Network (ATN) sites was combined with survey data of caregivers of children diagnosed with ASD. Caregivers completed instruments by proxy describing child health and completed the EQ-5D-3L and SF-6D preference-weighted instruments to describe their own health.
resultsThere was a strong correlation between the health utility scores of the two preference-weighted instruments (ρ = 0.6172, p < 0.001) measuring caregiver health-related quality of life. There was a similar correlation between both the SF-6D and EQ-5D-3L scores with a previously validated care-related quality of life measure (Care-related Quality of Life instrument [CarerQol-7D]) (ρ = 0.569, p < 0.001 and ρ = 0.541, p < 0.001, respectively). The mean SF-6D scores for caregivers differed significantly in relation to four of the five child health or behavior measures whereas the EQ-5D-3L differed for only two of them.
conclusionsHealth utility values of caregivers for children with ASD vary by the health characteristics of the child, suggesting significant potential for spillover effects. The comparison of the EQ-5D-3L and SF-6D demonstrated that both instruments can be used to estimate spillover effects of interventions to improve child health, but the SF-6D exhibited greater sensitivity to child health among children with ASD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.