Evidence map›Paper›PMID 30864004›Full record

ArticleJournal of ultrasound2019

Hepatocellular carcinoma tumor thrombus entering the inferior vena cava treated with percutaneous RF ablation: a case report.

Pietro Gatti, Antonio Giorgio, Emanuela Ciracì, Italia Roberto, Alessandro Anglani, Spano Sergio, Fernando Rizzello, Valentina Giorgio, Stefano Semeraro

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of ultrasound, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Pietro GattiInternal Medicine Division, Ostuni Hospital, Ostuni, BR, Italy.
Antonio GiorgioInterventional Ultrasound Unit, Tortorella Clinical Hospital, Salerno, Italy.
Emanuela CiracìInternal Medicine Division, Ostuni Hospital, Ostuni, BR, Italy.
Italia RobertoInternal Medicine Division, Ostuni Hospital, Ostuni, BR, Italy.
Alessandro AnglaniRadiodiagnostic Unit, Ostuni Hospital, Ostuni, BR, Italy.
Spano SergioInterventional Radiology Unit, Perrino Hospital, Brindisi, Italy.
Fernando RizzelloAnesthesiology and Reanimation Unit, Ostuni Hospital, Ostuni, BR, Italy.
Valentina GiorgioPediatric Gastroenterology Unit, Policlinico Gemelli, Sacred Heart University, Rome, Italy.
Stefano SemeraroInternal Medicine Division, Ostuni Hospital, Ostuni, BR, Italy. stefsem@libero.it.
Agostino Gemelli University Polyclinic · ITOspedale A. Perrino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHepatocellular carcinoma (HCC) is the most common form of liver cancer. In advanced cancer stages (metastatic disease and/or vascular invasion), the generally accepted standard of care is systemic therapy using sorafenib as first-line treatment and, recently, regorafenib and nivolumab as second-line treatment, but the quality of life and the prognosis of patients remain very poor. Our paper reports a case of US-guided radiofrequency ablation (RFA) of both intraparenchymal HCC and inferior vena cava tumor thrombus.

methodsWe treated a patient with HCC associated with tumor thrombus extending into vena cava after failure of sorafenib therapy using US-guided radiofrequency ablation (RFA).

resultsA good radiological and clinical response was observed in association with excellent tolerability. The patient has been followed up for 15 months from the ablation, is alive, and is in a good clinical condition without evidence of tumor recurrence.

conclusionThis is the first case in which this minimally invasive percutaneous procedure has been successfully used to treat an HCC thrombus entering the vena cava.

Indexed as

Neoplastic Cells, CirculatingRadiofrequency AblationVena Cava, InferiorCarcinoma, HepatocellularHumansLiver NeoplasmsMaleMiddle AgedSurgery, Computer-AssistedUltrasonography, InterventionalHepatocellular carcinomaLocoregional therapySorafenibTumor thrombusUS-guided radiofrequency ablation

Identifiers

PMID30864004
PMCPMC6704268
OpenAlexW2921743982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.