Evidence map›Paper›PMID 30863783›Full record

ReviewJournal of immunology research2019

The Relationship between Toll-like Receptors and

Lorena Elena Meliț, Cristina Oana Mărginean, Cristian Dan Mărginean, Maria Oana Mărginean

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. TLR2 variants andUpsala journal of medical sciences · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Autoimmune Gastritis andInternational journal of molecular sciences · 2025
    Review
  8. Article
  9. Review
  10. Frontiers in microbiology · 2025
    Review
  11. Article
  12. Article
  13. Sustained exposure to Helicobacter pylori induces immune tolerance by desensitizing TLR6.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024
    Article
  14. Review
  15. The immunopathogenesis ofFrontiers in microbiology · 2024
    Review
  16. Article
  17. Article
  18. Review of Phytochemical Potency as a Natural Anti-Molecules (Basel, Switzerland) · 2023
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lorena Elena MelițDepartment of Pediatrics, University of Medicine, Pharmacy, Sciences and Technology Tîrgu Mures, Gheorghe Marinescu Street No. 38, 540136, Romania.
Cristina Oana MărgineanDepartment of Pediatrics, University of Medicine, Pharmacy, Sciences and Technology Tîrgu Mures, Gheorghe Marinescu Street No. 38, 540136, Romania.ORCID 0000-0003-2119-1726
Cristian Dan MărgineanUniversity of Medicine, Pharmacy, Sciences and Technology of Tîrgu Mures, Gheorghe Marinescu Street No. 38, 540136, Romania.
Maria Oana MărgineanDepartment of Pediatrics, University of Medicine, Pharmacy, Sciences and Technology Tîrgu Mures, Gheorghe Marinescu Street No. 38, 540136, Romania.
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate immunity represents the first barrier against bacterial invasion. Toll-like receptors (TLRs) belong to the large family of pattern recognition receptors (PRRs), and their activation leads to the induction of inflammatory cytokines, chemokines, antigen-presenting molecules, and costimulatory molecules. Recent studies have focused on identifying the association between TLRs and

Indexed as

AnimalsEthnicityGastrointestinal DiseasesHelicobacter InfectionsHelicobacter pyloriHumansImmunity, InnateMicePolymorphism, GeneticReceptors, Pattern RecognitionRisk FactorsSignal TransductionStomach NeoplasmsToll-Like ReceptorsReceptors, Pattern RecognitionToll-Like Receptors

Identifiers

PMID30863783
PMCPMC6378784
OpenAlexW2913926246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.