Evidence map›Paper›PMID 30863764›Full record

ArticleWorld journal of clinical cases2019

Perioperative topical ascorbic acid for the prevention of phacoemulsification-related corneal endothelial damage: Two case reports and review of literature.

Chia-Yi Lee, Hung-Ta Chen, Yi-Jen Hsueh, Hung-Chi Chen, Chieh-Cheng Huang, Yaa-Jyuhn James Meir, Chao-Min Cheng, Wei-Chi Wu

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chia-Yi LeeDepartment of Ophthalmology, Show Chwan Memorial Hospital, Changhua 50093, Taiwan.
Hung-Ta ChenDepartment of Internal Medicine, Taipei City Hospital- Heping Branch, Taipei 10341, Taiwan.
Yi-Jen HsuehDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou 20012, Taiwan.
Hung-Chi ChenDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou 20012, Taiwan.
Chieh-Cheng HuangCenter for Tissue Engineering, Chang Gung Memorial Hospital, Linkou 20012, Taiwan.
Yaa-Jyuhn James MeirDepartment of Biomedical Sciences, College of Medicine Chang Gung University, Taoyuan 33305, Taiwan.
Chao-Min ChengCenter for Tissue Engineering, Chang Gung Memorial Hospital, Linkou 20012, Taiwan.
Wei-Chi WuDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou 20012, Taiwan.
Chang Bing Show Chwan Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current case report describes successful phacoemulsification with the aid of perioperative topical ascorbic acid (AA) in two patients with corneal endothelial disorders to prevent postoperative corneal endothelial decompensation. CASE SUMMARY: Two eyes of two patients underwent phacoemulsification with pre-existing corneal endothelial disorders including Fuchs corneal endothelial dystrophy (Patient 1) and endotheliitis (Patient 2). Topical AA was applied to both patients at least one month before and after with a frequency of four times per day. After the surgery, both eyes improved best-corrected visual acuity (BCVA) and there was limited human corneal endothelial cell loss without signs of corneal endothelial decompensation, such as deteriorated BCVA or persistent corneal edema during the follow-up of at least two years.

conclusionPerioperative administration of topical AA may be an alternative therapy to the triple procedure in patients expecting to undergo cataract surgery.

Indexed as

Ascorbic acidCase reportEndotheliitisFuchs corneal endothelial dystrophyHuman corneal endothelial cellPhacoemulsification

Identifiers

PMID30863764
PMCPMC6406191
OpenAlexW2920968391

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.