Evidence map›Paper›PMID 30863665›Full record

ArticleCentral Asian journal of global health2018

Detection of Hepatitis E Antibodies in Kazakhstan: A Pilot Study.

Francesca Cainelli, Gonzalo Hortelano, Baurzhan Negmetzhanov, Aigerim Ibrayeva, Kulpash Kaliaskarova, Denis Bulanin, Sandro Vento

Open access · diamondAbstract read
In one paragraph

Article in Central Asian journal of global health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Francesca CainelliDepartment of Medicine, School of Medicine, Nazarbayev University, Astana, Kazakhstan.
Gonzalo HortelanoDepartment of Biology, School of Science and Technology, Nazarbayev University, Astana, Kazakhstan.
Baurzhan NegmetzhanovDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana, Kazakhstan.
Aigerim IbrayevaDepartment of Medicine, School of Medicine, Nazarbayev University, Astana, Kazakhstan.
Kulpash KaliaskarovaHepatology Coordinating Center, Ministry of Health, Astana, Kazakhstan.
Denis BulaninDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana, Kazakhstan.
Sandro VentoDepartment of Medicine, School of Medicine, Nazarbayev University, Astana, Kazakhstan.
Nazarbayev University · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHepatitis E virus exposure is associated with sporadic cases of acute hepatitis and outbreaks in many countries worldwide. It is particularly dangerous for pregnant women, in whom the mortality rate is high. There are no previously published data reporting circulation of this virus in Kazakhstan.

methodsWe tested blood samples for IgG anti-hepatitis E virus antibodies in 199 Kazakh participants; of these 119 were workers at the EXPO 2017 building site in Astana, 35 were volunteers who got tested at the Astana City Hall on the World Hepatitis Day 2017, and 45 were volunteers who presented for screening at the Hepatogastroenterology Outpatient Clinic of the Republican Diagnostic Center, University Medical Center.

results11 (5.5%) individuals were positive for IgG anti-HEV antibodies, with a higher seroprevalence in males (7; 6.8%) vs females (4; 4.5%). The highest number of positive samples was in the 32-46 years age group.

conclusionsThis pilot study suggests that Hepatitis E virus has been circulating in Kazakhstan. Studies are needed to determine whether it continues to be present, which viral genotypes are involved and what are the best methodologies for preventing its spread.

Indexed as

anti-HEV antibodiesHepatitis EKazakhstan

Identifiers

PMID30863665
PMCPMC6393053
OpenAlexW2790354595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.