Evidence map›Paper›PMID 30863639›Full record

ArticlePulmonary medicine2019

Pulmonary Densitovolumetry Using Computed Tomography in Patients with Nontuberculous Mycobacteria: Correlation with Pulmonary Function Tests.

Patricia Gomes Cytrangulo De Marca, Telma Goldenberg, Fernanda Carvalho Queiroz Mello, Alysson Roncally Silva Carvalho, Alan Ranieri Medeiros Guimarães, Roberto Mogami, Agnaldo José Lopes

Abstract read
In one paragraph

Article in Pulmonary medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Review
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Patricia Gomes Cytrangulo De MarcaPost-Graduate Program in Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Telma GoldenbergPost-Graduate Program in Clinical Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Fernanda Carvalho Queiroz MelloPost-Graduate Program in Clinical Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Alysson Roncally Silva CarvalhoLaboratory of Respiration Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Alan Ranieri Medeiros GuimarãesLaboratory of Pulmonary Engineering, Biomedical Engineering Program, Alberto Luiz Coimbra Institute of Post-Graduation and Research in Engineering, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Roberto MogamiPost-Graduate Program in Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Agnaldo José LopesPost-Graduate Program in Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0001-8598-4878

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince nontuberculous mycobacterial pulmonary disease (NTM-PD) is a condition with increasing morbidity, a more detailed knowledge of radiological aspects and pulmonary function plays a relevant role in the diagnosis and appropriate therapeutic management of these patients.

objectivesThe purpose of this study was to evaluate changes in lung parenchyma through computed tomography (CT) densitometry and, secondarily, to analyze its correlation with pulmonary function testing (PFT) in patients with NTM-PD.

methodsThis is a cross-sectional study in which 31 patients with NTM-PD and 27 controls matched by sex, age, and body mass index underwent CT pulmonary densitovolumetry and pulmonary function tests including spirometry and body plethysmograph.

resultsBased on the total lung volume (TLV) and total lung mass (TLM) measurements, the cumulative mass ratios were calculated for 3% (M3), 15% (M15), 85% (M85), and 97% (M97) of the TLV. We also calculated the complement, which is represented by TLM (100%) minus the mass of 15% (C85) or 3% (C97) of the TLV. Patients with NTM-PD presented lower values of M3 and M15 than controls, with greater significant differences in the apical third and middle third measurements. Compared to controls, patients with NTM-PD showed higher values of C85 and C97, although significant differences were observed only in the basal third measurements. There were negative correlations of total lung capacity with M3 and M15 in the middle third and apical third measurements. There were positive correlations of residual volume and airway resistance with M3 at the apical third measurement.

conclusionsPatients with NTM-PD show reduced lung mass and increased lung mass in the apical and basal regions of the lungs, respectively. Furthermore, there is a relationship between lung mass measurements and pulmonary function parameters.

Indexed as

Lung Volume MeasurementsCase-Control StudiesCross-Sectional StudiesFemaleHumansLungMaleMiddle AgedMycobacterium Infections, NontuberculousNontuberculous MycobacteriaRespiratory Function TestsTomography, X-Ray Computed

Identifiers

PMID30863639
PMCPMC6377979

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