Evidence map›Paper›PMID 30863632›Full record

Trial reportJournal of obesity2019

Double-Blind, Randomized, Three-Armed, Placebo-Controlled, Clinical Investigation to Evaluate the Benefit and Tolerability of Two Dosages of IQP-AE-103 in Reducing Body Weight in Overweight and Moderately Obese Subjects.

Ralf Uebelhack, Udo Bongartz, Stephanie Seibt, Gordana Bothe, Pee Win Chong, Patricia De Costa, Natalia Wszelaki

Erratum issued 2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of obesity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03058367 nacompletednot on this map

Double-blind, Randomised, Three-armed, Placebo-controlled, Clinical Investigation to Evaluate the Benefit and Tolerability of Two Dosages of IQP-AE-103 in Reducing Body Weight in Overweight and Moderately Obese Subjects

TypeinterventionalSponsorInQpharm GroupRan2017 to 2017Enrolled108ConditionsOverweight, ObesityArmsIQP-AE-103 (330mg), IQP-AE-103 (165mg), Placebo
NCT04086797 nacompletednot on this map

Double-blind, Randomised, Placebo-controlled Study to Evaluate the Efficacy and Safety of IQP-AE-103 in Overweight and Moderately Obese Subjects

TypeinterventionalSponsorPerrigo CSCIRan2019 to 2021Enrolled178ConditionsOverweight, ObesityArmsIQP-AE-103, Placebo
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Effect ofInternational journal of molecular sciences · 2024
    Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Okra (Molecules (Basel, Switzerland) · 2021
    Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ralf Uebelhackanalyze & realize GmbH, Weißenseer Weg 111, 10369 Berlin, Germany.
Udo Bongartzanalyze & realize GmbH, Weißenseer Weg 111, 10369 Berlin, Germany.
Stephanie Seibtanalyze & realize GmbH, Waldseeweg 6, 13467 Berlin, Germany.
Gordana Botheanalyze & realize GmbH, Waldseeweg 6, 13467 Berlin, Germany.
Pee Win ChongZaluvida Corporate Sdn Bhd, E-16 Plaza Mont Kiara, 2 Jalan Kiara, 50480 Kuala Lumpur, Malaysia.ORCID 0000-0001-8973-864X
Patricia De CostaInQpharm Group Sdn Bhd, E-16 Plaza Mont Kiara, 2 Jalan Kiara, 50480 Kuala Lumpur, Malaysia.ORCID 0000-0001-9098-117X
Natalia WszelakiZaluvida Corporate Sdn Bhd, E-16 Plaza Mont Kiara, 2 Jalan Kiara, 50480 Kuala Lumpur, Malaysia.
Analyze & Realize (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study was performed to determine the efficacy and tolerability/safety of IQP-AE-103 on body weight reduction in overweight to moderately obese adults. Methods: A double-blind, randomized, placebo-controlled trial involved one hundred and eight subjects (BMI between 25 and 35 kg/m Results: After 12 weeks of intake, the high-dose IQP-AE-103 group had a significantly greater weight loss compared with the placebo (5.03 ± 2.50 kg vs. 0.98 ± 2.06 kg, respectively; Conclusions: These findings indicate that IQP-AE-103 could be an effective and safe weight loss intervention. This trial is registered with NCT03058367.

Indexed as

AbelmoschusAdultAnti-Obesity AgentsBody WeightDietary SupplementsDiet, ReducingDouble-Blind MethodFemaleHumansInulinMaleMiddle AgedObesityOverweightPhytotherapyTreatment OutcomeAnti-Obesity AgentsInulin

Identifiers

PMID30863632
PMCPMC6377993
OpenAlexW2911673627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.