Evidence map›Paper›PMID 30863626›Full record

ArticleJournal of ophthalmology2019

Jesús Barrio-Barrio, Elvira Bonet-Farriol, Marta Galdós, Susana Noval, Victoria Pueyo, Charles E Breeze, Jose Luis Santos, Belén Alfonso-Bartolozzi, Sergio Recalde, Ana Patiño-García

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Jesús Barrio-BarrioDepartment of Ophthalmology, Clínica Universidad de Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain.ORCID 0000-0002-0654-0249
Elvira Bonet-FarriolDepartment of Ophthalmology, Clínica Universidad de Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain.
Marta GaldósDepartment of Ophthalmology, Hospital de Cruces, 48903 Bilbao, Spain.
Susana NovalDepartment of Ophthalmology, Hospital Universitario La Paz, Autonomous University, IdiPaz, 28046 Madrid, Spain.
Victoria PueyoAragon Institute for Health Research (IIS Aragón), Ophthalmology Department, Miguel Servet University Hospital, 50009 Zaragoza, Spain.
Charles E BreezeUCL Cancer Institute, University College London, London WC1E 6BT, UK.
Jose Luis SantosDepartment of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, 8330077 Santiago, Chile.ORCID 0000-0003-2895-0369
Belén Alfonso-BartolozziDepartment of Ophthalmology, Clínica Universidad de Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain.
Sergio RecaldeDepartment of Ophthalmology, Clínica Universidad de Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain.
Ana Patiño-GarcíaDepartment of Pediatrics and Clinical Genetics Unit, Clínica Universidad de Navarra, Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain.
Clinica Universidad de Navarra · ESHospital de Cruces · ESHospital Universitario La Paz · ESInstituto de Investigación Sanitaria Aragón · ESPontificia Universidad Católica de Chile · CLUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEven though ocular refractive state is highly heritable and under strong genetic control, the identification of susceptibility genes remains a challenge. Several PURPOSE: Here, we assess the association of an

methodsAn observational prospective multicenter cross-sectional study was designed, including a total of 403 unrelated subjects comprising 188 hyperopic children (5 to 17 years) and 2 control groups: 52 emmetropic adolescents (13 to 17 years) and 163 emmetropic young adults (18 to 28 years). Each individual underwent a comprehensive eye examination including cycloplegic refraction, and topographic and ocular biometric analysis. Genomic DNA was extracted from oral swabs.

resultsNo association between rs12536657 and hyperopia was found through gender-adjusted logistic regression comparing the hyperopic children with either of the two control groups. Significant associations between mean topographic corneal curvature and rs12536657 for G/A (slope = +0.32; CI 95%: 0.04-0.60;

conclusionsOur results support a possible role for

Identifiers

PMID30863626
PMCPMC6378066
OpenAlexW2913015630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.