Evidence map›Paper›PMID 30863492›Full record

ArticleOncotarget2019

Broad-spectrum receptor tyrosine kinase inhibitors overcome

Ramona Graves-Deal, Galina Bogatcheva, Saba Rehman, Yuanyuan Lu, James N Higginbotham, Bhuminder Singh

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Analysis of EGFR binding hotspots for design of new EGFR inhibitory biologics.Protein science : a publication of the Protein Society · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Targeting RTK-PI3K-mTOR Axis in Gliomas: An Update.International journal of molecular sciences · 2021
    Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ramona Graves-DealDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Galina BogatchevaDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Saba RehmanDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Yuanyuan LuDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
James N HigginbothamDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Bhuminder SinghDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Vanderbilt University Medical Center · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Integrated approach to study early and late events in colonic neoplasia: mouse to manR35CA197570 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Robert J. Coffey · 2017 to 2026
$9.4M
NCI NIH HHS P30 CA068485NCI NIH HHS R35 CA197570NIDDK NIH HHS P30 DK058404
6 · The paper itself

Abstract

It is increasingly appreciated that 3D cultures are more predictive of

Indexed as

cetuximab resistancecolorectal cancerEGFRMETRTK inhibition

Identifiers

PMID30863492
PMCPMC6407678
OpenAlexW2914971500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.