Evidence map›Paper›PMID 30863405›Full record

ArticleFrontiers in immunology2019

Combination of Synthetic Long Peptides and XCL1 Fusion Proteins Results in Superior Tumor Control.

Natalia K Botelho, Benjamin O Tschumi, Jeffrey A Hubbell, Melody A Swartz, Alena Donda, Pedro Romero

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 39 citations in OpenAlex.

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  13. Dendritic Cell-Based Immunotherapy in Hot and Cold Tumors.International journal of molecular sciences · 2022
    Review
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  16. Immunogenicity of theVaccines · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Natalia K BotelhoDepartment of Fundamental Oncology, Faculty of Biology and Medicine, University of Lausanne, Epalinges, Switzerland.
Benjamin O TschumiDepartment of Fundamental Oncology, Faculty of Biology and Medicine, University of Lausanne, Epalinges, Switzerland.
Jeffrey A HubbellInstitute for Molecular Engineering, University of Chicago, Chicago, IL, United States.
Melody A SwartzInstitute for Molecular Engineering, University of Chicago, Chicago, IL, United States.
Alena DondaDepartment of Fundamental Oncology, Faculty of Biology and Medicine, University of Lausanne, Epalinges, Switzerland.
Pedro RomeroDepartment of Fundamental Oncology, Faculty of Biology and Medicine, University of Lausanne, Epalinges, Switzerland.
University of Lausanne · CHUniversity of Chicago · US

Funding

Paradoxical roles of tumor lymphangiogenesis on tumor immunity and implications for immunotherapy - Resubmission 01R01CA219304 · NCI · UNIVERSITY OF CHICAGO · PI SWARTZ, MELODY ANN · 2018 to 2022
$1.8M
NCI NIH HHS R01 CA219304
6 · The paper itself

Abstract

Cross-presenting Xcr1

Indexed as

Adjuvants, ImmunologicAnimalsCancer VaccinesCD8-Positive T-LymphocytesChemokines, CCHO CellsCricetinaeCricetulusDendritic CellsInterferon-gammaMelanoma, ExperimentalMice, Inbred C57BLMice, KnockoutOvalbuminPeptide FragmentsRecombinant Fusion ProteinsAdjuvants, ImmunologicCancer VaccinesChemokines, CInterferon-gammaOvalbuminPeptide FragmentsRecombinant Fusion ProteinsVaccines, SyntheticXCL1 protein, humanantigen cross-presentationsynthetic long peptidestherapeutic cancer vaccineXcl1Xcr1+ DC

Identifiers

PMID30863405
PMCPMC6399421
OpenAlexW2915189560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.