Evidence map›Paper›PMID 30863393›Full record

ReviewFrontiers in immunology2019

Structure-Function Relationships of C-Reactive Protein in Bacterial Infection.

Donald N Ngwa, Alok Agrawal

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Editorial: Biology of C-reactive protein.Frontiers in immunology · 2024
    Article
  12. C-Reactive Protein Is Not the Driver Factor in Ulcerative Colitis.Gastroenterology research and practice · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Inflammatory bowel disease biomarkers.Medicinal research reviews · 2022
    Review
  20. The Quest for a Child-Friendly Tuberculosis Triage Test.Journal of the Pediatric Infectious Diseases Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Donald N NgwaDepartment of Biomedical Sciences, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, United States.
Alok AgrawalDepartment of Biomedical Sciences, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, United States.
East Tennessee State University · US

Funding

Complement-mediated anti-pneumococcal functions of C-reactive proteinR56AI117730 · NIAID · EAST TENNESSEE STATE UNIVERSITY · PI AGRAWAL, ALOK · 2015 to 2015
$370k
NIAID NIH HHS R56 AI117730
6 · The paper itself

Abstract

One host defense function of C-reactive protein (CRP) is to protect against

Indexed as

Host-Pathogen InteractionsAnimalsBacterial InfectionsC-Reactive ProteinHumansPhosphorylcholinePneumococcal InfectionsProtein BindingStreptococcus pneumoniaeStructure-Activity RelationshipC-Reactive ProteinPhosphorylcholineC-reactive proteinfactor Hphosphocholinepneumococcal C-polysaccharideStreptococcus pneumoniae

Identifiers

PMID30863393
PMCPMC6400226
OpenAlexW2915648876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.