Evidence map›Paper›PMID 30863391›Full record

ArticleFrontiers in microbiology2019

MexXY Multidrug Efflux System Is More Frequently Overexpressed in Ciprofloxacin Resistant French Clinical Isolates Compared to Hospital Environment Ones.

Cristiano Serra, Bakhta Bouharkat, Aicha Tir Touil-Meddah, Stéphanie Guénin, Catherine Mullié

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. The emergence of pan-drug-resistantNew microbes and new infections · 2026
    Article
  3. TXA11114: Discovery of anAntibiotics (Basel, Switzerland) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Cristiano SerraLaboratoire des Agents Infectieux, Resistance et Chimiothérapie - EA 4294, UFR de Pharmacie, Université de Picardie Jules Verne, Amiens, France.
Bakhta BouharkatLaboratoire de Bioconversion, Génie Microbiologique et Sécurité Sanitaire N°145, Faculté des Sciences de la Nature et de la Vie, Université Mustapha Stambouli, Mascara, Algeria.
Aicha Tir Touil-MeddahLaboratoire de Bioconversion, Génie Microbiologique et Sécurité Sanitaire N°145, Faculté des Sciences de la Nature et de la Vie, Université Mustapha Stambouli, Mascara, Algeria.
Stéphanie GuéninCentre de Ressources Régionales en Biologie Moléculaire, UFR des Sciences, Université de Picardie Jules Verne, Amiens, France.
Catherine MulliéLaboratoire des Agents Infectieux, Resistance et Chimiothérapie - EA 4294, UFR de Pharmacie, Université de Picardie Jules Verne, Amiens, France.
Université Mustapha Stambouli de Mascara · DZAgents infectieux, résistance et chimiothérapie · FRCentre Hospitalier Universitaire Amiens-Picardie · FRUniversité de Picardie Jules Verne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modulation of the membrane permeability through a decrease in porin-mediated antibiotic entry and/or an increase in antibiotic efflux is one of the resistance mechanisms to antibiotics evolved by Gram-negative bacteria. To assess whether the outer membrane porin OprD and Resistance-Nodulation-Division (RND) efflux pumps were similarly expressed in 33 ciprofloxacin-resistant clinical strains of

Indexed as

efflux pumpenvironmentfluoroquinoloneoverexpressionPseudomonas aeruginosaresistance

Identifiers

PMID30863391
PMCPMC6399115
OpenAlexW2917758234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.