Evidence map›Paper›PMID 30863132›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2019

Identification of the

Ana Carolina Proença da Fonseca, Gabriella de Medeiros Abreu, Verônica Marques Zembrzuski, Mario Campos Junior, João Regis Ivar Carneiro, Fernanda Cristina C Mattos Magno, Eliane Lopes Rosado, José Firmino Nogueira Neto, Giselda Maria Kalil de Cabello, Pedro Hernán Cabello

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A hypothalamic pathway for Augmentor α-controlled body weight regulation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  6. Article
  7. Article
  8. A Rare Potential Pathogenic Variant in theDiabetes, metabolic syndrome and obesity : targets and therapy · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ana Carolina Proença da FonsecaHuman Genetics Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil, ana.proenca@ioc.fiocruz.br.
Gabriella de Medeiros AbreuHuman Genetics Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil, ana.proenca@ioc.fiocruz.br.
Verônica Marques ZembrzuskiHuman Genetics Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil, ana.proenca@ioc.fiocruz.br.
Mario Campos JuniorHuman Genetics Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil, ana.proenca@ioc.fiocruz.br.
João Regis Ivar CarneiroClementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Fernanda Cristina C Mattos MagnoInstitute of Nutrition Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Eliane Lopes RosadoInstitute of Nutrition Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
José Firmino Nogueira NetoDepartment of Pathology and Laboratory, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Giselda Maria Kalil de CabelloHuman Genetics Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil, ana.proenca@ioc.fiocruz.br.
Pedro Hernán CabelloHuman Genetics Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil, ana.proenca@ioc.fiocruz.br.
Fundação Oswaldo Cruz · BRUniversidade Federal do Rio de Janeiro · BRUniversidade do Estado do Rio de Janeiro · BRUniversidade Unigranrio · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsThis study comprised 157 adult participants, stratified according to the period of obesity onset. The first group included 97 patients with childhood-onset obesity (0-11 years) and the second group comprised 60 subjects with adolescence/youth-onset obesity (12-21 years). The entire coding region of

resultsAs a result, five previously described variants (Met1?, Ser36Thr, Val103Ile, Ile98=, and Phe202Leu) were identified. Met1? is a start lost codon variant, which affects the translation of

conclusionThis study showed the prevalence of

Indexed as

blood pressureMC4Rmutationsevere obesitystart lost

Identifiers

PMID30863132
PMCPMC6388727
OpenAlexW2915824745

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.