ArticleInternational journal of chronic obstructive pulmonary disease
COPD and the risk of mild cognitive impairment and dementia: a cohort study based on the Chinese Longitudinal Health Longevity Survey.
Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Population attributable fractions of a wide range of peripheral diseases for the burden of dementia.Nature human behaviour · 2026Pooled it
- Chronic obstructive pulmonary disease as a risk factor for cognitive impairment: a systematic review and meta-analysis.BMJ open respiratory research · 2024Pooled it
- Risk of dementia or cognitive impairment in COPD patients: A meta-analysis of cohort studies.Frontiers in aging neuroscience · 2022Pooled it
- Multidimensional cortical morphological alterations in COPD using explainable machine learning.iScience · 2026Article
- Article
- Unknotting the crosstalk between COPD and neuroinflammation.Journal of neuroinflammation · 2026Review
- Aberrant brain functional network in COPD patients with cognitive impairment: clinical manifestations, mechanisms and therapeutic strategies.Journal of neuroinflammation · 2025Review
- Article
- The association of sun-cured tobacco and cigarette use with global cognitive function, verbal fluency and memory in patients with chronic obstructive pulmonary disease: A cross-sectional study.Tobacco induced diseases · 2024Article
- Breathing on the mind: Treating dyspnea and anxiety symptoms with biofeedback in chronic lung disease - A qualitative analysis.Respiratory medicine · 2024Article
- Rural-Urban Differences in Mild Cognitive Impairment Among Patients with Chronic Obstructive Pulmonary Disease in ChengDu, China.International journal of chronic obstructive pulmonary disease · 2023Article
- Development of a Clinical Risk Score Prediction Tool for 5-, 9-, and 13-Year Risk of Dementia.JAMA network open · 2022Article
- Pulmonary function is associated with cognitive decline and structural brain differences.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- Association of chronic obstructive pulmonary disease with mild cognitive impairment and dementia risk: A systematic review and meta-analysis.World journal of clinical cases · 2022Article
- Prevalence and associated factors of cognitive impairment among the elderly population: A nationwide cross-sectional study in China.Frontiers in public health · 2022Article
- Association between pulmonary ventilatory function and mild cognitive impairment: A population-based study in rural China.Frontiers in public health · 2022Article
- Prevalence of Dementia in China in 2015: A Nationwide Community-Based Study.Frontiers in public health · 2021Article
- Article
- Influence of Comorbidities on the Survival of COPD Patients According to Phenotypes.International journal of chronic obstructive pulmonary disease · 2020Observational
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCOPD may lead to cognitive impairment or even dementia. However, the current conclusions are inconsistent with little evidence from prospective, large-sample studies. This study was designed to explore the association of COPD with mild cognitive impairment (MCI) and dementia risk based on a cohort study. PATIENTS AND
methodsAll participants were from the Chinese Longitudinal Health Longevity Survey (CLHLS) 2011/2012 waves. The follow-up survey was conducted in 2014 and the incidence of MCI and dementia were recorded.
resultsDuring the 3-year follow-up period, 712 new cases of MCI and 83 new cases of dementia were diagnosed. The incidence of MCI and dementia were higher in those with COPD than those without COPD at baseline. Cox analysis showed that the HRs of COPD for MCI and dementia incidence were 1.486 (95% CI: 1.207-1.855) and 1.896 (95% CI: 1.079-3.330), respectively after adjusting for related covariates. For different baseline smoking status, those who were current smokers had the highest HRs of COPD for MCI and dementia.
conclusionBaseline COPD was independently associated with increased risk of MCI and dementia incidence among Chinese elderly, and the association was more pronounced among those who were current smokers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.